Reber Justin, Tranel Daniel
Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, United States; Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, United States.
Department of Neurology, University of Iowa College of Medicine, Iowa City, IA, United States.
Handb Clin Neurol. 2019;163:147-164. doi: 10.1016/B978-0-12-804281-6.00008-2.
The frontal lobes contain a complex set of diverse anatomic regions that form multiple distinct, complex networks with cortical and subcortical regions. Damage to these cortical-subcortical networks can have dramatic behavioral consequences, ranging from apathy to impairments in executive functioning. This chapter provides a brief overview of the common syndromes caused by damage to the mediodorsal and dorsolateral prefrontal circuits, followed by a more detailed review of the syndrome-sometimes referred to as pseudopsychopathy or acquired sociopathy-associated with damage to the ventromedial prefrontal circuit.
额叶包含一组复杂多样的解剖区域,这些区域与皮质和皮质下区域形成多个不同的复杂网络。这些皮质 - 皮质下网络受损会产生显著的行为后果,从冷漠到执行功能受损不等。本章简要概述了由内侧背侧和背外侧前额叶回路损伤引起的常见综合征,随后更详细地回顾了与腹内侧前额叶回路损伤相关的综合征——有时被称为假性精神病或后天性反社会人格障碍。