PiM亚型的遗传情况。对151个家庭（共242名儿童）以及142对母婴进行的研究。
Inheritance of PiM subtypes. A study of 151 families with a total of 242 children and of 142 mother-child pairs.
作者信息
Cleve H, Patutschnick W, Strecker K, Nevo S
出版信息
Hum Hered. 1979;29(6):351-4. doi: 10.1159/000153071.
PMID:315911
Abstract
Pi phenotypes were classified by isoelectric focusing in sera of 151 families with a total of 242 children and in sera of 142 mother-child pairs. The six common subtypes of PiM are genetically determined by three alleles named PiM1, PiM2, and PiM3. No exceptions to the postulated mode of inheritance have been found. The possibility of further heterogeneity of the intermediate variant PiM3 is discussed.
摘要
通过等电聚焦对151个家庭（共242名儿童）的血清以及142对母婴的血清进行Pi表型分类。PiM的六种常见亚型由名为PiM1、PiM2和PiM3的三个等位基因遗传决定。尚未发现假定遗传模式的例外情况。文中讨论了中间变体PiM3进一步异质性的可能性。
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