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健康胎盘组织内源性矿物质的纳米分析特征:矿物质分布、组成和超微结构。

Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure.

机构信息

Laboratory for Particles Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, CH-9014, St Gallen, Switzerland.

出版信息

Analyst. 2019 Nov 18;144(23):6850-6857. doi: 10.1039/c9an01312a.

DOI:10.1039/c9an01312a
PMID:31591608
Abstract

Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.

摘要

尽管胎盘起着至关重要的作用,但它却是人体器官中研究最少的一个。最近的临床研究表明,胎盘钙化与母婴健康直接相关。本研究使用最先进的纳米分析特性揭示了妊娠年龄增长过程中形成的矿物质的独特特征,并为基于典型胎盘矿物质特征来识别临床环境中疾病风险的潜在标志物的研究铺平了道路。

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Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure.健康胎盘组织内源性矿物质的纳米分析特征:矿物质分布、组成和超微结构。
Analyst. 2019 Nov 18;144(23):6850-6857. doi: 10.1039/c9an01312a.
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The Role of Inorganics in Preeclampsia Assessed by Multiscale Multimodal Characterization of Placentae.通过胎盘的多尺度多模态表征评估无机物在子痫前期中的作用。
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