Laboratory for Particles Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, CH-9014, St Gallen, Switzerland.
Analyst. 2019 Nov 18;144(23):6850-6857. doi: 10.1039/c9an01312a.
Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.
尽管胎盘起着至关重要的作用,但它却是人体器官中研究最少的一个。最近的临床研究表明,胎盘钙化与母婴健康直接相关。本研究使用最先进的纳米分析特性揭示了妊娠年龄增长过程中形成的矿物质的独特特征,并为基于典型胎盘矿物质特征来识别临床环境中疾病风险的潜在标志物的研究铺平了道路。