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标准轴位与薄层冠状位扩散加权成像联合应用在急性脑干梗死诊断中的价值

Value of Combination of Standard Axial and Thin-Section Coronal Diffusion-weighted Imaging in Diagnosis of Acute Brainstem Infarction.

作者信息

Khaleel Nashwan I, Zghair Muna A G, Hassan Qays A

机构信息

Department of Radiology, Al-Yarmook Teaching Hospital, Baghdad, Iraq.

Division of Radiology, Department of Medicine, College of Medicine, Al-Mustansiriyah University, Baghdad, Iraq.

出版信息

Open Access Maced J Med Sci. 2019 Jul 28;7(14):2287-2291. doi: 10.3889/oamjms.2019.336. eCollection 2019 Jul 30.

DOI:10.3889/oamjms.2019.336
PMID:31592276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6765079/
Abstract

AIM

To determine the value of the combination of thin-section 3 mm coronal and standard axial DWI and their impact in facilitating the diagnosis of acute brainstem infarction.

METHODS

A cross-sectional study conducted from the 1st of April 2017 to the end of February 2018 on 100 consecutive patients (66% were male, and 34% were female) with isolated acute ischemic infarction in the brainstem. The abnormal MRI findings concerning the ischemic lesions were interpreted on standard axial 5 mm and thin-section coronal 3mm DWI.

RESULTS

The mean age of the studied group was 69.2 ± 4.3 for male and 72.3 ± 2.5 years. The standard axial DWI can diagnose 20%, 6.7% and 6.7% of the infarctions in midbrain, pons and medulla oblongata respectively, while both axial and thin coronal sections together can diagnose 80% of midbrain infarctions, 93.3% of pons infarctions and 93.3% of medulla oblongata infarctions. Furthermore, the thin section coronal 3 mm section can diagnose very smaller ischemic lesion volume in comparison to the standard axial 5mm section (3.4 ± 0.45 / cm versus 4.6 ± 0.23 / cm, P < 0.001).

CONCLUSION

The addition of thin-section coronal DWI can facilitate the detection of brainstem ischemic lesions. We suggest its inclusion in the stroke MRI protocol.

摘要

目的

确定3毫米薄层冠状位与标准轴位弥散加权成像(DWI)联合应用的价值及其对急性脑干梗死诊断的促进作用。

方法

2017年4月1日至2018年2月底对100例连续的孤立性急性脑干缺血性梗死患者进行横断面研究(66%为男性,34%为女性)。在标准轴位5毫米和薄层冠状位3毫米DWI上解读有关缺血性病变的异常MRI表现。

结果

研究组男性平均年龄为69.2±4.3岁,女性为72.3±2.5岁。标准轴位DWI分别能诊断中脑、脑桥和延髓梗死的20%、6.7%和6.7%,而轴位和薄层冠状位联合应用能诊断80%的中脑梗死、93.3%的脑桥梗死和93.3%的延髓梗死。此外,与标准轴位5毫米层面相比,3毫米薄层冠状位层面能诊断出体积更小的缺血性病变(3.4±0.45/cm对4.6±0.23/cm,P<0.001)。

结论

增加薄层冠状位DWI有助于检测脑干缺血性病变。我们建议将其纳入卒中MRI检查方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/a9d51c7e6638/OAMJMS-7-2287-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/e03abb7a9751/OAMJMS-7-2287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/b3651dd02421/OAMJMS-7-2287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/a9d51c7e6638/OAMJMS-7-2287-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/e03abb7a9751/OAMJMS-7-2287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/b3651dd02421/OAMJMS-7-2287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af60/6765079/a9d51c7e6638/OAMJMS-7-2287-g003.jpg

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Brainstem stroke: anatomy, clinical and radiological findings.
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Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study.与单独使用依达拉奉相比,用羟基自由基清除剂依达拉奉和氢气治疗急性脑干梗死部位时,脑磁共振成像指标得到改善。一项非对照研究。
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