Kaneda Kotaro, Yagi Takeshi, Todani Masaki, Nakahara Takashi, Fujita Motoki, Kawamura Yoshikatsu, Oda Yasutaka, Tsuruta Ryosuke
Advanced Medical Emergency and Critical Care Center Yamaguchi University Hospital Ube Yamaguchi Japan.
Acute Med Surg. 2019 May 22;6(4):371-378. doi: 10.1002/ams2.423. eCollection 2019 Oct.
To assess whether the outcomes of out-of-hospital cardiac arrest (OHCA) differ between patients treated at tertiary or secondary emergency medical facilities.
Data from the Japanese Association for Acute Medicine Out-of-Hospital Cardiac Arrest (JAAM-OHCA) registry between June 2014 and December 2015 were analyzed and compared between patients treated at tertiary (tertiary group) and secondary (secondary group) emergency medical facilities. The primary outcome of this study was a favorable neurological outcome at 1 and 3 months after OHCA, defined as a Glasgow-Pittsburgh cerebral performance category of 1 or 2.
Between June 2014 and December 2015, a total of 13,491 patients with OHCA were registered in the JAAM-OHCA registry. Of these, 12,836 were eligible in the present analysis, with 11,583 in the tertiary group and 1,253 in the secondary group. The proportions of patients with favorable neurological outcomes in the tertiary group were significantly higher than those in the secondary group at 1 (4.7% versus 2.0%, < 0.001) and 3 (3.5% versus 1.6%, < 0.001) months after OHCA. Even after adjusting for baseline characteristics of patients, treatment at a tertiary emergency medical facility was independently associated with favorable neurological outcomes at 1 (odds ratio, 2.856, 95% confidence interval, 1.429-5.710; = 0.003) and 3 (odds ratio, 2.462, 95% confidence interval, 1.203-5.042; = 0.014) months after OHCA.
The neurological outcomes of patients with OHCA treated at tertiary emergency medical facilities were better than those of patients treated at secondary emergency medical facilities.
评估在三级或二级急救医疗机构接受治疗的院外心脏骤停(OHCA)患者的预后是否存在差异。
分析并比较了2014年6月至2015年12月期间日本急性医学协会院外心脏骤停(JAAM-OHCA)登记处的数据,这些数据来自于在三级(三级组)和二级(二级组)急救医疗机构接受治疗的患者。本研究的主要结局是OHCA后1个月和3个月时良好的神经功能结局,定义为格拉斯哥-匹兹堡脑功能分类为1或2。
2014年6月至2015年12月期间,共有13491例OHCA患者登记在JAAM-OHCA登记处。其中,12836例符合本分析的条件,三级组有11583例,二级组有1253例。OHCA后1个月(4.7%对2.0%,<0.001)和3个月(3.5%对1.6%,<0.001)时,三级组良好神经功能结局患者的比例显著高于二级组。即使在调整患者的基线特征后,在三级急救医疗机构接受治疗与OHCA后1个月(优势比,2.856,95%置信区间,1.429 - 5.710;P = 0.003)和3个月(优势比,2.462,95%置信区间,1.203 - 5.042;P = 0.014)时良好的神经功能结局独立相关。
在三级急救医疗机构接受治疗的OHCA患者的神经功能结局优于在二级急救医疗机构接受治疗的患者。