Jain Ekta, Kini Lata, Alaggio Rita, Ranganathan Sarangarajan
Core Diagnostics, Gurgaon, Haryana, India.
Ospedale Pediatrico Bambino Gesu, Roma, Italy.
Int J Surg Pathol. 2020 May;28(3):306-309. doi: 10.1177/1066896919879497. Epub 2019 Oct 8.
Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare soft tissue neoplasm most commonly occurring in the distal extremities of adult patients. It is a low-grade neoplasm with high rate of local recurrence but low rate of metastasis. We describe a case of MIFS of eyeball in an infant. An enucleation surgery was performed, and on the basis of histopathological and immunohistochemical evaluation, a diagnosis of MIFS was rendered. Till date more than 400 cases of MIFS have been reported with only a single case report of MIFS in an adult in iris. To the best of our knowledge, ours is the first case of MIFS in the eye in a child. Considering its rarity in children and especially in an infant (this seems to be the youngest patient in the literature), close follow-up is essential as the biology of these lesions cannot be predicted.
黏液炎性纤维母细胞肉瘤（MIFS）是一种罕见的软组织肿瘤，最常见于成年患者的四肢远端。它是一种低级别肿瘤，局部复发率高但转移率低。我们描述了一例婴儿眼球的MIFS病例。进行了眼球摘除术，并根据组织病理学和免疫组织化学评估，做出了MIFS的诊断。迄今为止，已报道了400多例MIFS病例，仅有1例成人虹膜MIFS的病例报告。据我们所知，我们的病例是儿童眼部MIFS的首例。鉴于其在儿童尤其是婴儿中罕见（这似乎是文献中最年轻的患者），由于这些病变的生物学行为无法预测，密切随访至关重要。
