Gastroenterología, Centro Nacional de Cirugía de Mínimo Acceso, Cuba.
Investigaciones, Centro Nacional de Cirugía de Mínimo Acceso.
Rev Esp Enferm Dig. 2019 Nov;111(11):852-857. doi: 10.17235/reed.2019.5998/2018.
hemorrhagic radiation proctitis appears secondary to radiotherapy. Argon plasma is an effective, safe and easy-to-use technique with a relatively low cost.
to describe the short- and long-term response to argon plasma therapy in patients with hemorrhagic radiation proctitis.
an observational prospective study was performed of a series of 82 patients with hemorrhagic radiation proctitis, attended at the National Center for Minimally Invasive Surgery between 2010 and 2016. Summary measurements and a comparison of means (paired Student's t-test) for the final and initial hemoglobin levels were used. In addition, the Kaplan-Meier method was used to determine the rectal bleeding recurrence free time.
in the present study, 54.9% of cases required 1-3 argon sessions and 86.6% required 1-5 sessions to resolve the bleeding, with a median of 3.0 sessions. In addition, 4.9% of patients had proctalgia as a complication. There was an improvement in hemoglobin of 2 g/dl. Rectal bleeding recurrence occurred in 8.5% of the patients during the nine months after therapy. Bleeding recurrence free time at three, six and nine months was 98.8%, 96.3% and 91.5%, respectively. Short-term therapy response was observed in all patients and long-term response after one year of follow-up was 91.5%.
argon plasma coagulation shows a good short- and long-term response with few therapy sessions and a low rate of complications in patients with chronic hemorrhagic radiation proctitis.
出血性放射性直肠炎继发于放射治疗。氩等离子体是一种有效、安全且易于使用的技术，成本相对较低。
描述氩等离子体治疗对出血性放射性直肠炎患者的短期和长期疗效。
对 2010 年至 2016 年在国家微创外科中心就诊的 82 例出血性放射性直肠炎患者进行了一项观察性前瞻性研究。采用汇总测量和最终与初始血红蛋白水平的均值比较（配对学生 t 检验）。此外，还使用 Kaplan-Meier 方法确定直肠出血无复发时间。
在本研究中，54.9%的病例需要 1-3 次氩气治疗，86.6%的病例需要 1-5 次治疗才能止血，中位数为 3.0 次。此外，4.9%的患者出现直肠痛作为并发症。血红蛋白升高 2g/dl。治疗后 9 个月内有 8.5%的患者出现直肠出血复发。治疗后 3、6 和 9 个月的无出血复发时间分别为 98.8%、96.3%和 91.5%。所有患者均观察到短期治疗反应，随访 1 年后的长期反应为 91.5%。
氩等离子体凝固治疗慢性出血性放射性直肠炎，治疗次数少，并发症发生率低，具有良好的短期和长期疗效。
