Akbaş Yılmaz, Koker Alper, Erkek Nilgün
Hatay State Hospital, Department of Pediatrics, Hatay, Turkey.
Hatay State Hospital, Department of Pediatrics, Pediatric Intensive Care Unit, Hatay, Turkey, E-mail:
Pediatr Endocrinol Rev. 2019 Sep;17(1):35-40. doi: 10.17458/per.vol17.2019.ake.hyperphosphatemiaaffectsmortality.
Hypophosphatemia was previously shown to affect the duration of admission, mechanical ventilator requirements, mortality and morbidity during pediatric intensive care. Different from previous studies, our study was planned with the aim of showing whether hyperphosphatemia affects morbidity and mortality in pediatric intensive care patients as much as hypophosphatemia.
Patients' ages, genders, reason for admission, underlying diseases, phosphorus levels examined on admission and on the 1-4th and 5-10th-days, duration on mechanical ventilation, duration of admission, final status and PRISM and PELOD scores calculated in the first 24 hours of admission were recorded.
Mortality was distinctly higher for those who were hypophosphatemic and hyperphosphatemic compared to those who were normophosphatemic. The highest mortality was identified in those who were hyperphosphatemic on the 5-10th-days. PELOD scores were only significantly different according to admission phosphorus levels (p:0.04).
In our study, we identified that hyperphosphatemia is a serious problem as hypophosphatemia for patients who admitted to the PICU. Patients identified to be hyperphosphatemic on admission had a significantly higher PELOD score. The significant difference of hyperphosphatemia in terms of PELOD score is one of the important points shown in our study. It should not be forgotten that like hypophosphatemia, hyperphosphatemia may cause serious problems in pediatric intensive care patients.
先前的研究表明，低磷血症会影响小儿重症监护期间的住院时间、机械通气需求、死亡率和发病率。与以往研究不同的是，我们开展本研究的目的是探究高磷血症对小儿重症监护患者发病率和死亡率的影响是否与低磷血症一样大。
记录患者的年龄、性别、入院原因、基础疾病、入院时以及第1 - 4天和第5 - 10天检测的磷水平、机械通气时间、住院时间、最终状态以及入院后24小时内计算的PRISM和PELOD评分。
与血磷正常的患者相比，低磷血症和高磷血症患者的死亡率明显更高。第5 - 10天血磷高的患者死亡率最高。PELOD评分仅根据入院时的血磷水平有显著差异（p：0.04）。
在我们的研究中，我们发现对于入住儿科重症监护病房（PICU）的患者，高磷血症与低磷血症一样是一个严重问题。入院时被确定为高磷血症的患者PELOD评分显著更高。高磷血症在PELOD评分方面的显著差异是我们研究中显示的重要要点之一。不应忘记，与低磷血症一样，高磷血症可能在小儿重症监护患者中引发严重问题。
