• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名儿科患者轻度头部创伤后的QT间期延长

QT Prolongation After Minor Head Trauma in a Pediatric Patient.

作者信息

Mubayed Lamya, Romme Angela, Nguyen Hoang H

机构信息

Department of Pediatrics/Division of Cardiology, Rush University Medical College, Chicago, IL, USA.

出版信息

Pediatr Cardiol. 2020 Feb;41(2):414-417. doi: 10.1007/s00246-019-02213-0. Epub 2019 Oct 10.

DOI:10.1007/s00246-019-02213-0
PMID:31599347
Abstract

We report a case of QTc prolongation associated with mild concussion in a pediatric patient. An 11-year-old male presented to the emergency department after sustaining a head injury during football practice. He complained of headache and blurry vision. Physical examination was within normal apart from an irregular heart rhythm. Electrocardiogram (ECG) showed normal sinus rhythm with QTc (Bazett formula) 460 ms. The patient was diagnosed with concussion and referred for cardiology follow-up of the QTc. ECG the next day showed QTc 462 ms (heart rate 105 bpm) supine and 494 ms after suddenly standing up (heart rate 120 bpm). Family history was negative for sudden cardiac events. Exercise stress testing 1 week later showed a baseline QTc 462 ms and 488 ms at 4 min into recovery. Holter monitoring showed evidence of increased parasympathetic activity manifested by marked sinus arrhythmia. Repeated ECG, exercise stress testing, and Holter monitoring 3 months later showed normalized QTc values. His concussion symptoms were resolved at the time of repeat testing. Mild head trauma/concussion could be associated with prolonged QTc and abnormal cardiac repolarization. While these changes seem to be self-limiting, they remain a possible substrate for malignant arrhythmias. Recognition of these changes would lead to appropriate reassurance and/or precautions in the acute setting, especially in at-risk populations such as long QT syndrome patients.

摘要

我们报告了一例小儿患者中与轻度脑震荡相关的QTc延长病例。一名11岁男性在足球训练中头部受伤后被送往急诊科。他主诉头痛和视力模糊。体格检查除心律不齐外均正常。心电图(ECG)显示窦性心律正常,QTc(Bazett公式)为460毫秒。该患者被诊断为脑震荡,并被转诊至心脏病科对QTc进行随访。次日的心电图显示,仰卧位时QTc为462毫秒(心率105次/分),突然站立后为494毫秒(心率120次/分)。家族史中无心脏性猝死事件。1周后的运动负荷试验显示,基线QTc为462毫秒,恢复4分钟时为488毫秒。动态心电图监测显示存在副交感神经活动增强的证据,表现为明显的窦性心律不齐。3个月后重复进行心电图、运动负荷试验和动态心电图监测,结果显示QTc值恢复正常。重复检查时他的脑震荡症状已消失。轻度头部外伤/脑震荡可能与QTc延长和心脏复极异常有关。虽然这些变化似乎是自限性的,但它们仍然可能是恶性心律失常的潜在基础。认识到这些变化将有助于在急性期给予适当的安慰和/或采取预防措施,尤其是在长QT综合征患者等高危人群中。

相似文献

1
QT Prolongation After Minor Head Trauma in a Pediatric Patient.一名儿科患者轻度头部创伤后的QT间期延长
Pediatr Cardiol. 2020 Feb;41(2):414-417. doi: 10.1007/s00246-019-02213-0. Epub 2019 Oct 10.
2
Problems with Bazett QTc correction in paediatric screening of prolonged QTc interval.儿童长QTc间期筛查中Bazett QTc校正的问题。
BMC Pediatr. 2020 Dec 14;20(1):558. doi: 10.1186/s12887-020-02460-8.
3
QT prolongation and minor head trauma: a report of two cases.QT间期延长与轻度头部创伤:两例报告
Minerva Pediatr. 2006 Dec;58(6):575-7.
4
"QT clock" to improve detection of QT prolongation in long QT syndrome patients.采用“QT时钟”改善长QT综合征患者QT间期延长的检测。
Heart Rhythm. 2016 Jan;13(1):190-8. doi: 10.1016/j.hrthm.2015.08.037. Epub 2015 Aug 31.
5
Effects on repolarization using dynamic QT interval monitoring in long-QT patients following left cardiac sympathetic denervation.左心交感神经去神经支配后,采用动态QT间期监测对长QT综合征患者复极化的影响。
J Cardiovasc Electrophysiol. 2015 Apr;26(4):434-439. doi: 10.1111/jce.12609. Epub 2015 Feb 8.
6
Maximum QTc on Holter electrocardiography in children.儿童动态心电图检查中的最大QTc值。
Pediatr Int. 2018 Jun;60(6):507-512. doi: 10.1111/ped.13556.
7
Automated QT analysis on Holter monitors in pediatric patients can differentiate long QT syndrome from controls.对儿科患者动态心电图监测仪进行自动QT分析可将长QT综合征与对照组区分开来。
Pacing Clin Electrophysiol. 2018 Jan;41(1):50-56. doi: 10.1111/pace.13244. Epub 2018 Jan 8.
8
Literature review and pilot studies of the effect of QT correction formulas on reported beta2-agonist-induced QTc prolongation.QT校正公式对报告的β2受体激动剂诱导的QTc延长影响的文献综述和初步研究。
Clin Ther. 2006 Apr;28(4):582-90. doi: 10.1016/j.clinthera.2006.04.010.
9
Effect of change in posture and exercise on repolarization in patients with long QT syndrome with HERG channel mutations.姿势改变和运动对携带HERG通道突变的长QT综合征患者复极化的影响。
Can J Cardiol. 2005 Jan;21(1):33-8.
10
QTc interval on 24-hour holter monitor: To trust or not to trust?24 小时动态心电图的 QTc 间期:可信还是不可信?
Ann Noninvasive Electrocardiol. 2022 Jan;27(1):e12899. doi: 10.1111/anec.12899. Epub 2021 Oct 24.

引用本文的文献

1
Trauma, a Matter of the Heart-Molecular Mechanism of Post-Traumatic Cardiac Dysfunction.创伤,心脏问题——创伤后心功能障碍的分子机制。
Int J Mol Sci. 2021 Jan 13;22(2):737. doi: 10.3390/ijms22020737.

本文引用的文献

1
Cardioautonomic instability following a sports-related concussion in a 20-year-old male.一名20岁男性在与运动相关的脑震荡后出现心脏自主神经功能不稳定。
Int J Cardiol. 2014 Apr 1;172(3):e511-2. doi: 10.1016/j.ijcard.2014.01.095. Epub 2014 Jan 24.
2
Increased QT interval variability in 3 recently concussed athletes: an exploratory observation.3 名新近脑震荡运动员 QT 间期变异增加:探索性观察。
J Athl Train. 2011 May-Jun;46(3):230-3. doi: 10.4085/1062-6050-46.3.230.
3
Corrected QT Interval in Children With Brain Death.脑死亡儿童的校正QT间期
Pediatr Cardiol. 2010 Oct;31(7):1064-9. doi: 10.1007/s00246-010-9766-x. Epub 2010 Aug 20.
4
QT prolongation and minor head trauma: a report of two cases.QT间期延长与轻度头部创伤:两例报告
Minerva Pediatr. 2006 Dec;58(6):575-7.
5
QTc dispersion in children with severe head trauma.重度颅脑损伤患儿的QTc离散度
Pediatr Emerg Care. 2005 Oct;21(10):658-61. doi: 10.1097/01.pec.0000181427.25342.e0.
6
ECG changes in pediatric patients with severe head injury.重度颅脑损伤患儿的心电图变化
J Neurosurg Anesthesiol. 2003 Jul;15(3):270-3. doi: 10.1097/00008506-200307000-00017.
7
Uncoupling of the autonomic and cardiovascular systems in acute brain injury.急性脑损伤中自主神经系统与心血管系统的解偶联。
Am J Physiol. 1998 Oct;275(4):R1287-92. doi: 10.1152/ajpregu.1998.275.4.R1287.
8
Beat-to-beat QT interval variability: novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy.逐搏QT间期变异性:缺血性和非缺血性扩张型心肌病复极不稳定的新证据。
Circulation. 1997 Sep 2;96(5):1557-65. doi: 10.1161/01.cir.96.5.1557.