Department of Neurosurgery, Tong Ji Hospital, Tong Ji University School of Medicine, Shanghai, China -
Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
J Neurosurg Sci. 2021 Oct;65(5):518-523. doi: 10.23736/S0390-5616.19.04759-3. Epub 2019 Oct 7.
To investigate the risk factors of preoperative and postoperative treatment for trigone ventricular meningioma and the clinical efficacy of microsurgical resection of the neoplasm using the parieto-occipital approach.
Forty-seven trigone ventricular meningiomas were resected using the parieto-occipital approach in one institute from January 2015 to January 2019. Patients were postoperative followed up for 3 months to 3 years. Karnofsky performance status (KPS) and Glasgow Coma Scale (GCS) were used to assess patient's performance status and consciousness. Clinical data including patients' characteristics, surgical procedure, and postoperative management were retrospectively analyzed.
Microsurgery achieved total removal of the tumor in 46 cases with no obvious residue (97.9%), and subtotal removal in 1 case (2.1%). No deaths occurred. Preoperative symptoms of neurology were significantly improved. There was a significant difference in preoperative KPS and postoperative KPS (P<0.05). No difference was found in GCS. Compared to patients with peritumoral brain edema (PTBE), KPS of patients without PTBE was significantly increased (P<0.05).
PTBE may be a risk factor for preoperative neurological symptoms. Furthermore, the parieto-occipital approach is a safe and effective surgical approach in resecting trigone ventricular meningioma.
探讨三角区脑室脑膜瘤术前术后治疗的危险因素，以及顶枕入路显微切除肿瘤的临床疗效。
2015 年 1 月至 2019 年 1 月，一家医院采用顶枕入路切除 47 例三角区脑室脑膜瘤。术后随访 3 个月至 3 年。卡氏功能状态评分（KPS）和格拉斯哥昏迷评分（GCS）用于评估患者的功能状态和意识。回顾性分析患者的临床资料，包括患者的特征、手术过程和术后处理。
46 例肿瘤全切除，无明显残留（97.9%），1 例次全切除（2.1%）。无死亡病例。术前神经症状明显改善。术前 KPS 和术后 KPS 差异有统计学意义（P<0.05）。GCS 无差异。与有瘤周水肿（PTBE）的患者相比，无 PTBE 的患者 KPS 明显升高（P<0.05）。
PTBE 可能是术前神经症状的危险因素。此外，顶枕入路是切除三角区脑室脑膜瘤的安全有效手术入路。
