Kepes Edith R, Duncalf Deryck
Albert Einstein College of Medicine, Pain Treatment Center, Montefiore Medical Center, and Albert Einstein College of Medicine, Department of Anesthesiology, Montefiore Medical Center, Bronx, NY 10467 U.S.A.
Pain. 1985 May;22(1):33-47. doi: 10.1016/0304-3959(85)90146-0.
Low back pain and sciatica have been treated with peridural local anesthetics for over 80 years and with epidural and subarachnoid steroid injections for a quarter of a century. This review surveyed the literature concerning the evolution, pathophysiology, complications and results of this type of therapy. The volume injected and the method used vary with different physicians and no standard has been established. Good results from this treatment which vary from 20 to 95% decrease on long-term follow up. Statistical significance is absent if compared with other forms of therapy. It is the authors' opinion that the rationale for the use of spinal local analgesics or steroids or intramuscular steroids has not been scientifically proven. Complications with the use of subarachnoid steroids are sufficiently serious that this form of therapy should be condemned. In this age of accountability it is imperative that therapies with questionable benefits should be critically evaluated.
硬膜外局部麻醉药用于治疗腰痛和坐骨神经痛已有80多年历史,而硬膜外和蛛网膜下腔注射类固醇已有25年历史。本综述调查了有关此类治疗的演变、病理生理学、并发症及结果的文献。注射量和使用方法因医生而异,尚未确立标准。这种治疗的良好效果在长期随访中下降幅度从20%到95%不等。与其他治疗形式相比,缺乏统计学意义。作者认为,使用脊髓局部镇痛药、类固醇或肌肉注射类固醇的理论依据尚未得到科学证实。使用蛛网膜下腔类固醇的并发症非常严重,这种治疗形式应受到谴责。在这个问责制时代,必须对益处存疑的治疗方法进行严格评估。