Kinetics of digestive enzyme stability in solid state I: application of Weibull distribution function to solid-state enzyme inactivation.

The Weibull distribution function was applied to solid-state enzyme inactivation. On Weibull probability paper (within a narrow range), the plots of the accumulated inactivation ratio of each enzyme versus time regressed to a straight line. The parameters m and k, which correspond to the type and rate of the type and rate of the inactivation, were characteristic of each enzyme. The effect of temperature and parameter reproducibility are discussed.