力致变色蛋白-聚合物杂化水凝胶用于可视化机械应变。
Mechano-chromic protein-polymer hybrid hydrogel to visualize mechanical strain.
机构信息
Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zürich, Vladimir-Prelog-Weg 4, 8093 Zürich, Switzerland.
出版信息
Soft Matter. 2019 Nov 27;15(46):9388-9393. doi: 10.1039/c9sm00380k.
PMID:31609367
Abstract
In a proof-of-concept study, a mechano-chromic hydrogel was synthesized here, via chemoenzymatic click conjugation of fluorophore-labeled fibronectin into a synthetic hydrogel co-polymers (i.e., poly-N-isopropylacrylamide/polyethylene glycol). The optical FRET response could be tuned by macroscopic stretch.
摘要
在一项概念验证研究中，通过化学酶点击反应将荧光标记的纤维连接蛋白偶联到合成水凝胶共聚物（即聚 N-异丙基丙烯酰胺/聚乙二醇）中，合成了一种机械变色水凝胶。宏观拉伸可以调节光 FRET 响应。
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