Department of Neurology, University of Colorado Denver, Denver, Colorado.
Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
J Palliat Med. 2020 Mar;23(3):415-421. doi: 10.1089/jpm.2019.0507. Epub 2019 Oct 15.
The diagnosis of an aggressive, primary brain tumor is life altering for those affected and too often portends a poor prognosis. Despite decades of research, neither a cure nor even a therapy that reliably and dramatically prolongs survival has been found. Fortunately, there are a number of treatments that may prolong the life of select brain tumor patients although the symptom burden can sometimes be high. This article brings together neuro-oncologists, neurologists, and palliative care (PC) physicians to help shine a light on these diseases, their genetics, treatment options, and the symptoms likely to be encountered both from the underlying illness and its treatment. We hope to increase the understanding that PC teams have around these illnesses to improve care for patients and families.
对于受影响的人来说,诊断出侵袭性原发性脑肿瘤会改变他们的生活,而且往往预示着预后不良。尽管经过几十年的研究,仍然没有找到治愈方法,甚至没有一种能够可靠地显著延长生存期的治疗方法。幸运的是,有许多治疗方法可以延长某些脑肿瘤患者的生命,尽管症状负担有时会很高。本文汇集了神经肿瘤学家、神经学家和姑息治疗(PC)医生,以帮助阐明这些疾病及其遗传、治疗选择,以及从潜在疾病及其治疗中可能出现的症状。我们希望提高 PC 团队对这些疾病的认识,以改善对患者和家庭的护理。