Influence of the electrical activity of muscle upon the excitability of neighbouring nerve.

Starting from studies concerned with the electrical interaction between adjacent nerve fibres, experiments were carried out to investigate the different subthreshold effects of the electrical activity of muscle upon the neighbouring nerve. The results obtained on frog's sciatic-gastrocnemius preparations show that electrical muscle activity has an influence upon the excitability of the nerve in contact with the muscle. The results support the assumption that electrical muscle activity could play an additional role in the regulatory mechanism of the excitatory processes in nerve and muscle functions.