Tschernjawsky G J, Pletschkowa E K
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Sep;211(3):235-41. doi: 10.1007/BF02387429.
The authors studied morphological changes in eleven ciliary ganglions. Seven ganglions were obtained from four corpses of patients with primary glaucoma in different stages, and four control ganglions were obtained from corpses of healthy people. The ciliary ganglion neurons of healthy subjects demonstrated age-related changes revealing nucleus shift toward the periphery, atypical hairy Kahal neurons, nerve fiber irritation phenomena, and other effects. The stage-dependent changes observed included: devastation areas, reactive proliteration around prolapsed neurons, nerve fiber degeneration, and hemorrhages. Maturing glaucomatous nerve cells and fiber degeneration also grew in proportion. In absolute glaucoma, ganglion cells were not present in ganglions. The authors believe that the existence of age-dependent structural changes in ciliary ganglia shows that ciliary ganglia are responsible for neurotropic innervation of eye membranes and participate in the glaucomatous process.
作者研究了11个睫状神经节的形态学变化。7个神经节取自不同病程阶段的4例原发性青光眼患者的尸体，4个对照神经节取自健康人的尸体。健康受试者的睫状神经节神经元呈现出与年龄相关的变化，包括细胞核向周边移位、非典型毛细胞型卡哈尔神经元、神经纤维刺激现象及其他影响。观察到的与病程阶段相关的变化包括：破坏区域、脱垂神经元周围的反应性增殖、神经纤维变性和出血。成熟的青光眼性神经细胞和纤维变性也按比例增加。在绝对期青光眼中，神经节内不存在神经节细胞。作者认为，睫状神经节中存在与年龄相关的结构变化表明，睫状神经节负责眼膜的神经营养性支配并参与青光眼的发病过程。
