Di S, Bell W H, Mannai C, Seale N S, Hurt W C, Taylor J, Waite D E
Division of Oral and Maxillofacial Surgery, University of Texas Health Science Center, Dallas.
Oral Surg Oral Med Oral Pathol. 1988 Apr;65(4):379-86. doi: 10.1016/0030-4220(88)90348-9.
Transient pulpal vascular ischemia and direct injury to the apices of the teeth have been implicated as the causes of degenerative and atrophic pulpal changes in experimental animals after Le Fort I osteotomy despite the presence of collateral circulation. The long-term clinical effect of these pathologic changes in human teeth has not been studied. Seventeen maxillary third molar teeth from 10 patients whose postsurgical follow-up ranged from 6 months to 78 months (mean, 40 months) were extracted. The long-term biologic effects of Le Fort I osteotomy on the pulp and on the development of teeth were retrospectively evaluated with clinical and standard histologic techniques. Normal teeth from patients who were not operated on were used as controls. Histologic examination revealed an intact pulpal circulation and minimal pathologic changes in the pulpal tissue. Clinical and radiographic studies showed that the growing teeth developed normally after surgery. The Le Fort I downfracture procedure had little discernible long-term effect on the pulp and on the development of human third molar teeth.
尽管存在侧支循环,但在实验动物中,短暂的牙髓血管缺血和牙齿根尖的直接损伤被认为是勒福Ⅰ型截骨术后牙髓发生退行性和萎缩性变化的原因。这些病理变化在人类牙齿中的长期临床影响尚未得到研究。从10例患者中拔除了17颗上颌第三磨牙,术后随访时间为6个月至78个月(平均40个月)。采用临床和标准组织学技术,对勒福Ⅰ型截骨术对牙髓和牙齿发育的长期生物学效应进行了回顾性评估。将未接受手术患者的正常牙齿用作对照。组织学检查显示牙髓循环完整,牙髓组织病理变化轻微。临床和影像学研究表明,生长中的牙齿在手术后发育正常。勒福Ⅰ型下颌骨截骨术对人类第三磨牙的牙髓和发育几乎没有明显的长期影响。