Department of Nursing, Fu Jen Catholic University Hospital, New Taipei City.
Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei.
Biol Res Nurs. 2020 Jan;22(1):34-44. doi: 10.1177/1099800419881210. Epub 2019 Oct 21.
Autonomic dysfunction, cognitive impairment, and psychological distress are associated with poorer prognosis in patients with acute ischemic stroke (AIS). Heart rate variability (HRV) biofeedback (BF) improves autonomic dysfunction, cognitive impairment, and psychological distress in other patient populations, but its effect in patients with AIS is still unclear.
This study investigated the effects of an HRVBF intervention on autonomic function, cognitive impairment, and psychological distress in patients with AIS.
In this randomized, controlled, single-blind trial, patients with AIS were randomly assigned to the experimental or control group. The experimental group received four HRVBF training sessions. The control group received usual care. Repeated measures of HRV, mini-mental status examination (MMSE), and Hospital Anxiety and Depression Scales (HADS) were collected prior to and at 1 and 3 months postintervention.
A total of 35 patients completed the study (19 experimental, 16 control). HRV and HADS significantly improved in the experimental group ( < .001) but not in the control group. Likewise, only the experimental group showed significant improvements in HRV, MMSE, and HADS over time ( < .05).
HRVBF is a promising intervention for improving autonomic function, cognitive impairment, and psychological distress in patients with AIS. More studies of HRVBF interventions are needed to further optimize the effects of HRVBF on autonomic, cognitive, and psychological function in patients with AIS.
自主神经功能障碍、认知障碍和心理困扰与急性缺血性脑卒中（AIS）患者的预后较差有关。心率变异性（HRV）生物反馈（BF）可改善其他患者群体的自主神经功能障碍、认知障碍和心理困扰，但在 AIS 患者中的效果尚不清楚。
本研究旨在探讨 HRV BF 干预对 AIS 患者自主功能、认知障碍和心理困扰的影响。
这是一项随机、对照、单盲试验，将 AIS 患者随机分配到实验组或对照组。实验组接受 4 次 HRV BF 训练，对照组接受常规护理。在干预前和干预后 1 个月和 3 个月分别采集 HRV、简易精神状态检查（MMSE）和医院焦虑抑郁量表（HADS）的重复测量数据。
共有 35 名患者完成了研究（实验组 19 名，对照组 16 名）。实验组的 HRV 和 HADS 显著改善（ <.001），而对照组则没有。同样，只有实验组在 HRV、MMSE 和 HADS 方面显示出随时间的显著改善（ <.05）。
HRV BF 是改善 AIS 患者自主功能、认知障碍和心理困扰的有前途的干预措施。需要更多的 HRV BF 干预研究来进一步优化 HRV BF 对 AIS 患者自主、认知和心理功能的影响。
