Xiang Xiaochao, Jiao Fenglong, Zhang Yangjun, Qian Xiaohong, Qin Weijie
Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), State Key Laboratory of Proteomics, Beijing 102206, China.
Se Pu. 2019 Nov 8;37(11):1135-1141. doi: 10.3724/SP.J.1123.2019.04041.
With the increasing depth of proteomic identification, quantitative accuracy and increasing analytical speed, new challenges are being encountered in the development of proteomics methods. Traditional proteomics methods are time-consuming and have low sensitivity and poor accuracy; hence, they do not satisfy the new demands in proteomics research. Preparation of novel materials with specific functions via chemical and biochemical routes or by methods based on electricity, magnetism, heat, and photoirradiation is the key to overcome the limitations of traditional analytical techniques and promote active research in the field of proteomics. This paper reviews the recent advances in the application of functional materials in proteomics researches.
随着蛋白质组学鉴定深度的增加、定量准确性的提高以及分析速度的加快，蛋白质组学方法的发展正面临新的挑战。传统蛋白质组学方法耗时且灵敏度低、准确性差，因此无法满足蛋白质组学研究的新需求。通过化学和生物化学途径或基于电、磁、热和光辐射的方法制备具有特定功能的新型材料，是克服传统分析技术局限性并推动蛋白质组学领域积极研究的关键。本文综述了功能材料在蛋白质组学研究中的应用进展。
