两例伴有t(11;22)(q24;q12)易位的软组织原发性外周神经上皮瘤新病例。

Two new cases of primary peripheral neuroepithelioma of soft tissue with translocation t(11;22)(q24;q12).

作者信息

López-Ginés C, Pellín A, Llombart-Bosch A

机构信息

Department of Pathology, University of Valencia, Medical School, Spain.

出版信息

Cancer Genet Cytogenet. 1988 Jul 15;33(2):291-7. doi: 10.1016/0165-4608(88)90037-4.

DOI:10.1016/0165-4608(88)90037-4

PMID:3164249

Abstract

A direct cytogenetic analysis was performed on tumor samples obtained from two patients with clinical and histopathologic diagnosis of primary peripheral neuroepithelioma. Both tumors presented the translocation t(11;22)(q24;q12). These results confirm those previously obtained by other authors and suggest a common histogenetic origin for this tumor with Ewing's sarcoma and Askin's tumor, in which the same translocation has been described.

摘要

对两名经临床和组织病理学诊断为原发性外周神经上皮瘤的患者的肿瘤样本进行了直接细胞遗传学分析。两个肿瘤均呈现t(11;22)(q24;q12)易位。这些结果证实了其他作者先前获得的结果，并提示该肿瘤与尤文肉瘤和Askin瘤有共同的组织发生学起源，在后者中也描述了相同的易位。