University of Michigan Medical School, Ann Arbor, MI.
Department of Anesthesiology, Michigan Medicine, Ann Arbor, MI.
Spine (Phila Pa 1976). 2020 Mar 15;45(6):407-413. doi: 10.1097/BRS.0000000000003285.
Systematic review.
We systematically reviewed the level of clinical evidence presented at Cervical Spine Research Society annual meetings from 2008 through 2017.
The Cervical Spine Research Society is dedicated to advancing knowledge of the cervical spine to promote evidence-based care. Research presented at these meetings impacts clinical practice.
A total of 774 paper abstracts presented at Cervical Spine Research Society (CSRS) annual meetings were independently assessed by two reviewers. Reviewers designated a clinical level of evidence (LOE) to each included abstract from level I to level IV based on criteria set forth by the Oxford Centre for Evidence-Based Medicine. Reviewer agreement was assessed using Cohens Kappa coefficient (k) and disagreements were discussed until a consensus was reached. Wilcoxon rank sum test was used to assess for differences in LOE grades. Chi-squared testing was used to assess nonrandom changes in level of evidence and in excluded studies.
A total of 583 abstracts were included. Over the last 10 CSRS meetings, 5.15% of presentations were level I, 27.8% level II, 27.4% level III, and 39.6% level IV. The average LOE from 2008 to 2017 was 3.02 (median = 3). Additionally, 49.7% were therapeutic studies, 37.6% prognostic studies, and 12.7% diagnostic studies. When comparing the first 5 years (2008-2012) to the last 5 years (2013-2017), we observed a significant increase in Level II (P = 0.007) evidence and a corresponding decrease in level IV evidence (P < 0.001). The average LOE improved from 3.14 (2008-2012) to 2.91 (2013-2017); there was a significant improvement in LOE between the two periods (P = 0.001).
Emphasis on evidence-based medicine within cervical spine research has positively influenced the clinical level of evidence disseminated at CSRS annual meetings between 2008 and 2017. Continued focus on higher quality Level I studies is warranted.
系统评价。
我们系统地回顾了 2008 年至 2017 年期间颈椎研究学会年会上呈现的临床证据水平。
颈椎研究学会致力于推进颈椎知识的发展,以促进循证护理。这些会议上呈现的研究影响临床实践。
两名评审员独立评估了在颈椎研究学会(CSRS)年会上提交的总共 774 篇论文摘要。根据牛津循证医学中心规定的标准,评审员将每个纳入的摘要指定为临床证据水平(LOE)从 I 级到 IV 级。使用 Cohen's Kappa 系数(k)评估评审员的一致性,并在达成共识之前讨论分歧。Wilcoxon 秩和检验用于评估 LOE 等级的差异。卡方检验用于评估证据水平和排除研究的非随机变化。
共纳入 583 篇摘要。在过去的 10 次 CSRS 会议中,5.15%的演讲为 I 级,27.8%为 II 级,27.4%为 III 级,39.6%为 IV 级。2008 年至 2017 年的平均 LOE 为 3.02(中位数=3)。此外,49.7%为治疗性研究,37.6%为预后性研究,12.7%为诊断性研究。比较前 5 年(2008-2012 年)和后 5 年(2013-2017 年),我们观察到 II 级(P=0.007)证据显著增加,而 IV 级证据相应减少(P<0.001)。LOE 平均值从 3.14(2008-2012 年)提高到 2.91(2013-2017 年);两个时期之间的 LOE 有显著提高(P=0.001)。
颈椎研究中对循证医学的重视积极影响了 2008 年至 2017 年期间在 CSRS 年会上传播的临床证据水平。需要继续关注更高质量的 I 级研究。
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