Leisser Christoph, Zandieh Shahin, Hirnschall Nino, Findl Oliver
Vienna Institute of Research in Ocular Surgery, Hanusch-Krankenhaus, Wien, Österreich.
Abteilung für Radiologie und Nuklearmedizin, Hanusch-Krankenhaus, Wien, Österreich.
Klin Monbl Augenheilkd. 2020 Aug;237(8):972-975. doi: 10.1055/a-0972-9886. Epub 2019 Oct 25.
Retinal artery occlusion (RAO) is caused by embolic occlusion of retinal arteries. Previous strokes in the medical history were reported in up to 20% of patients. According to data from a computational blood flow analysis based on magnetic resonance imaging of a patient with RAO, about 90% of ascending emboli are washed into the brain, leaving speculations about further embolic sources for RAO, such as plaques or stenosis of the ophthalmic artery. The aim of this study was to examine the reduced caliber of the ophthalmic artery in magnetic resonance angiography (MRA).
An analysis of a prospective case series of 9 patients with newly diagnosed RAO, presenting at the outpatient department. Magnetic resonance angiography of the brain, including the ophthalmic artery and carotid siphon was performed in all patients and evaluated by an experienced radiologist also specialised in neuroradiology. Outcomes were compared to an age-matched control group of 9 patients without RAO.
Four of 9 patients (44.4%) had a reduced caliber of the ophthalmic artery, two only at the side of RAO and another two bilateral. One of these cases also had a severe steno-occlusive disease of the internal carotid artery in the MRA, being in accordance with the results from duplex-sonography of the internal carotid artery. None of the patients in the control group had any signs of stenosis of the ophthalmic artery.
Reduced caliber of the ophthalmic artery in MRA is present in almost half of patients with RAO and indicates that steno-occlusive disease of the ophthalmic artery could be a possible source of emboli, causing RAO.
视网膜动脉阻塞(RAO)是由视网膜动脉的栓塞性阻塞引起的。既往病史中曾有中风的患者比例高达20%。根据一项基于RAO患者磁共振成像的计算血流分析数据,约90%的上行栓子被冲入大脑,这引发了对RAO其他栓子来源的猜测,如眼动脉斑块或狭窄。本研究的目的是在磁共振血管造影(MRA)中检查眼动脉管径变窄情况。
对9例新诊断为RAO的门诊患者进行前瞻性病例系列分析。所有患者均进行了包括眼动脉和颈动脉虹吸部的脑部磁共振血管造影,并由一位经验丰富的、专门从事神经放射学的放射科医生进行评估。将结果与9例无RAO的年龄匹配对照组进行比较。
9例患者中有4例(44.4%)眼动脉管径变窄,2例仅在RAO侧,另外2例双侧变窄。其中1例在MRA中还存在颈内动脉严重狭窄闭塞性病变,这与颈内动脉双功超声检查结果一致。对照组中无一例患者有眼动脉狭窄的迹象。
几乎一半的RAO患者MRA显示眼动脉管径变窄,这表明眼动脉狭窄闭塞性病变可能是导致RAO的栓子来源。