Department of Pediatric Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, TX, USA; Departments of Anesthesiology and Pediatrics, Baylor College of Medicine, 6551 Main St. E 1940, Houston, TX 77030-3411, USA.
Department of Pediatric Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, TX, USA; Departments of Anesthesiology and Pediatrics, Baylor College of Medicine, 6551 Main St. E 1940, Houston, TX 77030-3411, USA.
Clin Perinatol. 2019 Dec;46(4):657-671. doi: 10.1016/j.clp.2019.08.003. Epub 2019 Aug 26.
Neurodevelopmental outcomes after neonatal congenital heart surgery are significantly influenced by brain injury detectable by MRI imaging techniques. This brain injury can occur in the prenatal and postnatal periods even before cardiac surgery. Given the significant incidence of new MRI brain injury after cardiac surgery, much work is yet to be done on strategies to detect, prevent, and treat brain injury in the neonatal period in order to optimize longer-term neurodevelopmental outcomes.
新生儿先天性心脏病手术后的神经发育结果受到可通过 MRI 成像技术检测到的脑损伤的显著影响。这种脑损伤可在心脏手术之前的产前和产后期间发生。鉴于心脏手术后新出现 MRI 脑损伤的发生率很高,仍需要开展大量工作来制定策略,以便在新生儿期检测、预防和治疗脑损伤,从而优化长期神经发育结果。