Zanke B W, Johnston J B, Israels L G
Department of Medicine, University of Manitoba, Winnipeg, Canada.
Cancer. 1988 Sep 1;62(5):954-7. doi: 10.1002/1097-0142(19880901)62:5<954::aid-cncr2820620518>3.0.co;2-3.
Two patients who had both B-cell chronic lymphocytic leukemia (CLL) and dyserythropoiesis are described. One patient (Case 2) had both CLL and dyserythropoiesis. Erythrodysplasia developed in the other patient (Case 1) after treatment for CLL with alkylating agents and 2'-deoxycoformycin. The management of these patients and the possible mechanisms responsible for the development of dyserythropoiesis in CLL are discussed.
本文描述了两名同时患有B细胞慢性淋巴细胞白血病(CLL)和红细胞生成异常的患者。一名患者(病例2)同时患有CLL和红细胞生成异常。另一名患者(病例1)在使用烷化剂和2'-脱氧助间型霉素治疗CLL后出现了红细胞发育异常。文中讨论了这些患者的治疗方法以及CLL中红细胞生成异常发生的可能机制。