Protin Caroline, Abravanel Florence, Alric Laurent, Tavitian Suzanne, Obéric Lucie, Izopet Jacques, Martin-Blondel Guillaume, Ysebaert Loic
Hematology Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
Laboratory of Virology, CHU Purpan, Toulouse, France.
Open Forum Infect Dis. 2019 Jul 28;6(9):ofz345. doi: 10.1093/ofid/ofz345. eCollection 2019 Sep.
Ibrutinib is an oral first-in-class Bruton's tyrosine kinase inhibitor approved for the therapy of various B-cell lymphoid malignancies. Among ibrutinib-related infections, viral hepatitis are poorly described. We report our single-center experience with 4 cases of chronic hepatitis E virus infection and their management with ribavirin.
依鲁替尼是一种口服的一流布鲁顿酪氨酸激酶抑制剂，被批准用于治疗各种B细胞淋巴瘤。在与依鲁替尼相关的感染中，病毒性肝炎的描述较少。我们报告了我们单中心对4例戊型肝炎病毒慢性感染病例及其使用利巴韦林治疗的经验。
