Department of Health Sciences, Lakehead University, Thunder Bay, Ontario, Canada.
Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Brain Inj. 2020;34(2):195-202. doi: 10.1080/02699052.2019.1682670. Epub 2019 Oct 29.
Post-concussion syndrome refers to the adverse group of symptoms following a mild traumatic brain injury (mTBI). The Rivermead post-concussion syndrome questionnaire (RPQ) is a common clinical tool for assessing baseline post-concussion syndrome symptomology; however, it is unknown if scores on this questionnaire are associated with future disability. Therefore, the goal of this study was to determine the association between baseline RPQ scores and future disability in older adults with mTBI. This study used a prospective cohort design, using the RPQ to measure baseline post-concussion syndrome symptomatology. Disability at 6 months was measured using the Glasgow Outcome Scale-Extended (GOSE; disability), short-form 12 (SF-12; physical and mental quality of life), and self-reported recovery. Linear and logistic models adjusted for confounding factors were estimated using 200 bootstrapped samples. Individuals with higher levels of baseline symptomatology were more likely to have poor GOSE scores (RR = 2.13, 95% CI [1.51, 2.31]) and self-reported recovery (RR = 2.64, 95% CI [1.31, 8.98]) 6 months later. High levels of baseline symptomatology may be associated with overall disability and individual perceptions of recovery 6 months post-MTBI. While the RPQ is valid in assessing a patient's post-concussive symptoms following mTBI, it may not predict long-term physical or mental health in older adults.
脑震荡后综合征是指轻度创伤性脑损伤(mTBI)后的不良症状群。Rivermead 脑震荡后综合征问卷(RPQ)是评估脑震荡后综合征症状基线的常用临床工具;然而,尚不清楚该问卷的分数是否与未来的残疾有关。因此,本研究的目的是确定基线 RPQ 评分与 mTBI 老年患者未来残疾之间的关联。本研究采用前瞻性队列设计,使用 RPQ 测量基线脑震荡后综合征症状。使用格拉斯哥结局量表扩展版(GOSE;残疾)、短式 12 项健康调查(SF-12;身体和精神生活质量)和自我报告的恢复情况来测量 6 个月时的残疾。使用 200 个 bootstrap 样本调整混杂因素后,估计了线性和逻辑模型。基线症状水平较高的个体更有可能出现 GOSE 评分较差(RR=2.13,95%CI[1.51,2.31])和自我报告的恢复较差(RR=2.64,95%CI[1.31,8.98])6 个月后。基线时较高的症状水平可能与 6 个月后 mTBI 患者的整体残疾和个人对恢复的感知有关。虽然 RPQ 可有效评估 mTBI 后患者的脑震荡后症状,但它可能无法预测老年人的长期身体或心理健康。