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对 1488 例患有疼痛性颞下颌关节紊乱的患者进行表型分析及其与主观睡眠质量的相关性:分层医学的关键步骤。

Phenotyping 1488 patients with painful temporomandibular disorders and its relevance to subjective sleep quality: A key step for stratified medicine.

机构信息

Department of Orofacial Pain and Oral Medicine, College of Dentistry, Dankook University, Cheonan, South Korea.

出版信息

Cranio. 2021 Nov;39(6):491-501. doi: 10.1080/08869634.2019.1682750. Epub 2019 Oct 29.

DOI:10.1080/08869634.2019.1682750
PMID:31662051
Abstract

: To investigate biopsychosocial characteristics and sleep quality among three TMD phenotypes and to identify the influential factors on sleep quality among those patients.: Retrospective data from chart review and self-reported questionnaires included demographics, the Brief Pain Inventory, the Pain CatastropPain Prospective Evaluation and Risk Assessmenthizing Scale, the Symptom Check List-90 Revised, and the Pittsburgh Sleep Quality Index.: A total of 1488 patients with painful TMD (female, 63.8%) were included and stratified into three groups: joint pain (n = 570), muscle pain (n = 542), and joint-muscle combined pain (n = 376). There were significant differences among demographic characteristics, pain experience, pain catastrophizing, and psychological distress of the three groups. Poor sleep quality presented in 78.4% of all patients. Sleep quality was significantly associated with TMD phenotypes, sex, and a helplessness component of pain catastrophizing.: This patient-centered and stratified approach will allow clinicians to come one step closer to personalized medicine.

摘要

目的

探讨三种颞下颌关节紊乱病(TMD)表型的心理社会特征和睡眠质量,并确定这些患者睡眠质量的影响因素。

方法

通过病历回顾和自我报告问卷收集人口统计学资料、简明疼痛量表、疼痛灾难化量表、症状清单 90 修订版和匹兹堡睡眠质量指数。共纳入 1488 例有疼痛性 TMD 患者(女性,63.8%),并分为三组:关节痛(n=570)、肌痛(n=542)和关节-肌痛混合痛(n=376)。三组患者在人口统计学特征、疼痛体验、疼痛灾难化和心理困扰方面存在显著差异。所有患者中有 78.4%存在睡眠质量差的情况。睡眠质量与 TMD 表型、性别和疼痛灾难化的无助成分显著相关。

结论

这种以患者为中心和分层的方法将使临床医生更接近个性化医疗。

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A comparative analysis of older patients with chewing difficulties due to temporomandibular disorders and tooth loss.颞下颌关节紊乱和牙齿缺失导致咀嚼困难的老年患者的比较分析。
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Associations between obstructive sleep apnea and painful temporomandibular disorder: a systematic review.
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