Maniar Arpita, Jakati Saumya, Kaliki Swathi
Ocular Oncology, LV Prasad Eye Institute, Hyderabad, India.
Ophthalmic Pathology, LV Prasad Eye Institute, Hyderabad, India.
BMJ Case Rep. 2019 Oct 30;12(10):e231376. doi: 10.1136/bcr-2019-231376.
A 1-day-old child was brought to the clinic for evaluation of enlarged right eye (OD). On examination, OD showed buphthalmos with diffuse scleral melanocytosis, fleshy blackish-brown extrascleral mass with corneal extension, and secondary glaucoma. Anterior segment evaluation revealed darkly pigmented iris and fundus evaluation OD revealed a darkly pigmented choroidal lesion. The left eye was within normal limits. A clinical diagnosis of choroidal melanocytoma with ocular melanocytosis was made. Enucleation OD followed by orbital implant was performed. Histopathology showed features of diffuse ocular melanocytosis involving limbus, iris, ciliary body, choroid, sclera, optic nerve head, optic nerve sheath, along with choroidal melanocytoma with extrascleral tumour extension. We presume that choroidal melanocytoma may have arisen from ocular melanocytosis.
一名1日龄婴儿因右眼（OD）肿大被带到诊所进行评估。检查发现，右眼表现为牛眼，伴有弥漫性巩膜黑素沉着症，有肉质黑褐色巩膜外肿物并向角膜延伸，以及继发性青光眼。前段评估显示虹膜色素沉着深，眼底评估右眼显示脉络膜色素沉着深的病变。左眼正常。临床诊断为脉络膜黑素细胞瘤合并眼部黑素沉着症。对右眼进行了眼球摘除术，随后植入了眼眶植入物。组织病理学显示弥漫性眼部黑素沉着症的特征，累及角膜缘、虹膜、睫状体、脉络膜、巩膜、视神经乳头、视神经鞘，同时伴有脉络膜黑素细胞瘤并伴有巩膜外肿瘤延伸。我们推测脉络膜黑素细胞瘤可能起源于眼部黑素沉着症。
