Kelland M D, Asdourian D, Kelland D Z
Department of Psychology, Wayne State University, Detroit, MI 48202.
Behav Brain Res. 1988 Sep 1;30(1):1-13. doi: 10.1016/0166-4328(88)90002-2.
Electrical stimulation of the caudate-putamen (Cd-Pt) in anesthetized adult male rats was used to determine the nature and extent of the control exerted by the Cd-Pt over the following neck and shoulder muscles: the trapezius, biventer cervicis, rectus capitis and scalenus dorsalis. Unilateral Cd-Pt stimulation resulted in a pattern of muscle responses marked by immediate inhibition of ipsilateral spontaneous activity and subsequent excitation of contralateral activity. Lesions of the substantia nigra pars reticulata blocked the excitation in 3 of the 4 muscles, while globus pallidus lesions had equivocal results. However, control ablations of the frontoparietal motor cortex, which blocked excitation in all muscles, and kainic acid lesions of the Cd-Pt, which had no effect on excitation, suggested that the excitation of muscle activity can only be attributed to the stimulation of corticofugal fibers passing through this region (i.e. the Cd-Pt). The inhibition of spontaneous activity does appear to be attributable to stimulation of the Cd-Pt.
在麻醉的成年雄性大鼠中，通过电刺激尾状核 - 壳核（Cd - Pt）来确定Cd - Pt对以下颈部和肩部肌肉的控制性质和程度：斜方肌、颈二腹肌、头直肌和背斜角肌。单侧Cd - Pt刺激导致肌肉反应模式，其特征是立即抑制同侧自发活动，随后激发对侧活动。黑质网状部损伤阻断了4块肌肉中3块的激发，而苍白球损伤的结果不明确。然而，额叶顶叶运动皮层的对照消融阻断了所有肌肉的激发，而Cd - Pt的 kainic 酸损伤对激发没有影响，这表明肌肉活动的激发只能归因于穿过该区域（即Cd - Pt）的皮质传出纤维的刺激。自发活动的抑制似乎确实归因于Cd - Pt的刺激。
