Distribution and drug resistance of pathogenic bacteria in emergency patients.

BACKGROUND

Antibiotic resistance has become a global threat for human health, calling for rational use of antibiotics.

AIM

To analyze the distribution and drug resistance of the bacteria, providing the prerequisite for use of antibiotics in emergency patients.

METHODS

A total of 2048 emergency patients from 2013 to 2017 were enrolled. Their clinical examination specimens were collected, followed by isolation of bacteria. The bacterial identification and drug susceptibility testing were carried out.

RESULTS

A total of 3387 pathogens were isolated. The top six pathogens were (660 strains), (436 strains), (347 strains), (338 strains), (237 strains), and (207 strains). The isolation rates of these pathogens decreased year by year except , which increased from 7.1% to 12.1%. is a widely-resistant strain, with multiple resistances to imipenem, ciprofloxacin, minocycline and tigecycline. The had high resistance rates to levofloxacin, penicillin G, and tetracycline. But the susceptibility of it to vancomycin and tigecycline were 100%. had high resistance rates to imipenem, cefoperazone/sulbactam, amikacin, and ciprofloxacin, with the lowest resistance rate to tigecycline. The resistance rates of to cefoperazone/sulbactam and imipenem were higher, with the resistance rate to amikacin below 10%. Besides, had high resistance rates to ciprofloxacin and cefoperazone/sulbactam and low resistance rates to imipenem, amikacin, and tigecycline.

CONCLUSION

The pathogenic bacteria isolated from the emergency patients were mainly , , , , , and . The detection rates of drug-resistant bacteria were high, with different bacteria having multiple drug resistances to commonly used antimicrobial agents, guiding the rational use of drugs and reducing the production of multidrug-resistant bacteria.