Laboratorio de Biología de la Reproducción, UMF, FES Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla, Edo. de México, México.
Laboratorio de Biología de la Reproducción, UMF, FES Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Tlalnepantla, Edo. de México, México.
Horm Behav. 2020 Jan;117:104611. doi: 10.1016/j.yhbeh.2019.104611. Epub 2019 Nov 7.
Most mammal studies on the neuroendocrine mechanisms of territorial aggression have demonstrated that testosterone (T) is required for the display of territorial aggression. However, the relationship between T and aggression is more complex and may be modulated by social factor. The aim of this study was to determine the role of T in territorial aggression in the Mongolian gerbil (Meriones unguiculatus), and the effect of social factors on the modulation of this behavior. The relationship between T and territorial aggression was analyzed using castration and T replacement in two social contexts: male-male and male-female cohabitation. Plasma T concentrations in males of all groups were quantified by radioimmunoassay (RIA). T concentrations were compared using two-way ANOVA. Only sham-castrated and castrated males with T replacement in male-female cohabitation showed aggression, whereas castrated gerbils in the same condition were not aggressive. This indicates that T is the hormone that maintains territorial aggression, but mating is a modulator stimulus. The modulator effect of mating in territorial aggression was associated with an increase in T, but it seems that other mechanisms are involved in the regulation of this behavior, since castrated males with T replacement in the male-male cohabitation did not exhibit aggression, although they had T concentrations as high as these males that received the same treatment, but that cohabited with a female. These results suggest that T is involved in the mechanisms that regulate territorial aggression in the male Mongolian gerbil, and that the cohabitation with a female modulates this behavior.
大多数关于领地攻击的神经内分泌机制的哺乳动物研究表明，睾酮（T）是展示领地攻击所必需的。然而，T 与攻击的关系更为复杂，可能受到社会因素的调节。本研究旨在确定 T 在蒙古沙鼠（Meriones unguiculatus）领地攻击中的作用，以及社会因素对这种行为的调节作用。通过在两种社会环境下对雄性进行阉割和 T 替代，分析了 T 与领地攻击之间的关系：雄性-雄性和雄性-雌性同居。使用放射免疫测定法（RIA）对所有组别的雄性的血浆 T 浓度进行定量。使用双因素方差分析比较 T 浓度。只有在雄性-雌性同居中进行 T 替代的假阉割和阉割雄性才表现出攻击性，而处于相同条件下的阉割沙鼠则没有攻击性。这表明 T 是维持领地攻击的激素，但交配是一种调节刺激。交配在领地攻击中的调节作用与 T 的增加有关，但似乎涉及其他机制来调节这种行为，因为在雄性-雄性同居中进行 T 替代的阉割雄性虽然 T 浓度与接受相同治疗但与雌性同居的雄性一样高，但并未表现出攻击性。这些结果表明，T 参与了调节雄性蒙古沙鼠领地攻击的机制，而与雌性同居调节了这种行为。
