Hirst Cara Stella, White S, Siek T, Gasparik A
Anthropology Department, University College London, London, UK.
University College London, Institute of Archaeology, London, UK.
Surg Radiol Anat. 2020 Jan;42(1):91-94. doi: 10.1007/s00276-019-02350-4. Epub 2019 Oct 31.
This report details an unusual case of a human sternal developmental abnormality of an anatomical specimen part of the skeletal collection curated by University College London, Anthropology Department skeletal collection. This rarely reported developmental abnormality is caused by the non-fusion of lateral ossification centres in the sternebrae, resulting in the mesosternum having a honeycomb-like appearance. Sternal defects are typically underreported in the clinical literature as many cases being asymptomatic that they are typically diagnosed incidentally, as such there is a dearth in our current understanding of the development and anatomical variants of the sternum. Although in recent years, large-scale CT studies have investigated the prevalence of sternal developmental abnormalities, these studies have not reported sternal defects similar to the individual presented in this report. While most sternal defects are clinically uneventful, the lack of awareness of these variants can result in misinterpretation of radiological and pathological findings as such an understanding of anatomical variants even when asymptomatic is vital.
本报告详细介绍了伦敦大学学院人类学系骨骼收藏中的一具骨骼标本所呈现的人类胸骨发育异常的罕见病例。这种鲜有报道的发育异常是由胸骨节段外侧骨化中心未融合所致,导致胸骨体呈现蜂窝状外观。临床文献中对胸骨缺陷的报道通常较少,因为许多病例无症状,通常是偶然诊断出来的,因此我们目前对胸骨发育和解剖变异的了解存在不足。尽管近年来大规模CT研究调查了胸骨发育异常的患病率,但这些研究并未报告与本报告中个体相似的胸骨缺陷。虽然大多数胸骨缺陷在临床上并无大碍,但对这些变异缺乏认识可能导致对放射学和病理学结果的误解,因此即使无症状,了解解剖变异也至关重要。