Center for Mass Spectrometry, Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, NJ, 07030, USA.
Waters Corporation, Wilmslow, UK.
J Am Soc Mass Spectrom. 2019 Dec;30(12):2704-2710. doi: 10.1007/s13361-019-02339-8. Epub 2019 Oct 31.
Previous investigations have evaluated the efficacy of anions such as NO, Cl Br, CHCOO, and CFCOO as additives to generate or enhance mass spectrometric signals from explosives under plasma ionization conditions. The results of this study demonstrate that for detecting nitramine-class explosives, such as 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) and 1,3,5,7-tetranitro-1,3,5,7-tetrazacyclooctane (HMX), 1,4-benzoquinone (BQ) is a highly effective and efficient dopant. When used in conjunction with ambient-pressure negative-ion helium-plasma ionization (HePI), 1,4-benzoquinone readily captures an electron, forming an abundant molecular anion (m/z 108), which upon exposure to vapors of RDX and HMX generates adduct ions of m/z 330 and 404, respectively. The signal level recorded for RDX upon adduction to the radical anion of 1,4-benzoquinone under our experimental conditions was significantly higher than that realized by chloride adduction using dichloromethane (DCM) as the dopant.
先前的研究已经评估了阴离子（如 NO、Cl、Br、CHCOO 和 CFCOO）作为添加剂在等离子体电离条件下生成或增强爆炸物质谱信号的效果。本研究的结果表明，对于检测硝胺类炸药（如 1,3,5-三硝基六氢-1,3,5-三嗪（RDX）和 1,3,5,7-四硝基-1,3,5,7-四氮杂环辛烷（HMX）），1,4-苯醌（BQ）是一种非常有效和高效的掺杂剂。当与常压负离子氦等离子体电离（HePI）结合使用时，1,4-苯醌容易捕获一个电子，形成丰富的分子阴离子（m/z 108），当暴露于 RDX 和 HMX 的蒸气中时，分别生成 m/z 330 和 404 的加合物离子。在我们的实验条件下，1,4-苯醌的自由基阴离子与 RDX 加合时记录的信号水平明显高于使用二氯甲烷（DCM）作为掺杂剂时氯加合的信号水平。
