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马松肿瘤表现为左额叶脑实质内出血,导致妊娠期严重表达性失语:病例报告。

Masson's tumor presenting as a left frontal intraparenchymal hemorrhage resulting in severe expressive aphasia during pregnancy: case report.

作者信息

Sankey Eric W, Hynes Jenna S, Komisarow Jordan M, Maule Jake, Griffin Andrew S, Dotters-Katz Sarah K, Mitchell Courtney J, Friedman Allan H

机构信息

Departments of1Neurosurgery.

2Obstetrics and Gynecology.

出版信息

J Neurosurg. 2019 Nov 1;134(1):189-196. doi: 10.3171/2019.8.JNS191767. Print 2021 Jan 1.

DOI:10.3171/2019.8.JNS191767
PMID:31675720
Abstract

Intravascular papillary endothelial hyperplasia (IPEH), commonly known as Masson's tumor, is a benign lesion that manifests as an excessive proliferation of endothelial cells within a vessel wall. IPEH is extremely rare in the brain, with only 36 intracranial cases previously described in the literature. It is commonly mistaken for more malignant pathologies, such as angiosarcoma. Careful histopathological examination is required for diagnosis, as no clinical or radiographic features are characteristic of this lesion. In this first published case of intracranial IPEH presenting during pregnancy, the authors describe a 32-year-old female with a left frontal intraparenchymal hemorrhage resulting in complete expressive aphasia at 28 weeks 6 days' gestation. An MRI scan obtained at a local hospital demonstrated an area of enhancement within the hemorrhage. The patient underwent a left frontoparietal craniotomy for hematoma evacuation and gross-total resection (GTR) of an underlying hemorrhagic mass at 29 weeks' gestation. This case illustrates the importance of multidisciplinary patient care and the feasibility of intervention in the early third trimester with subsequent term delivery. While GTR of IPEH is typically curative, the decision to proceed with surgical treatment of any intracranial lesion in pregnancy must balance maternal stability, gestational age, and suspected pathology.

摘要

血管内乳头状内皮增生(IPEH),通常称为马松瘤,是一种良性病变,表现为血管壁内内皮细胞的过度增殖。IPEH在脑部极为罕见,文献中此前仅描述过36例颅内病例。它常被误诊为更具恶性的病变,如血管肉瘤。诊断需要仔细的组织病理学检查,因为该病变没有特征性的临床或影像学表现。在这例首次发表的妊娠期颅内IPEH病例中,作者描述了一名32岁女性,在妊娠28周6天时因左侧额叶脑实质内出血导致完全性运动性失语。当地医院的MRI扫描显示出血区内有强化区域。该患者在妊娠29周时接受了左额顶开颅血肿清除术及对潜在出血性肿块的全切除(GTR)。本病例说明了多学科患者护理的重要性以及在妊娠晚期进行干预并随后足月分娩的可行性。虽然IPEH的GTR通常具有治愈性,但对于妊娠期任何颅内病变进行手术治疗的决定必须权衡母体稳定性、孕周和疑似病变情况。

相似文献

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Masson's tumor presenting as a left frontal intraparenchymal hemorrhage resulting in severe expressive aphasia during pregnancy: case report.马松肿瘤表现为左额叶脑实质内出血,导致妊娠期严重表达性失语:病例报告。
J Neurosurg. 2019 Nov 1;134(1):189-196. doi: 10.3171/2019.8.JNS191767. Print 2021 Jan 1.
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引用本文的文献

1
Case report: Multiple brain intravascular papillary endothelial hyperplasia: incidence, diagnostic challenges, and management approach.病例报告:多发性脑内血管乳头状内皮增生症:发病率、诊断挑战及处理方法
Front Neurol. 2023 Apr 20;14:1115325. doi: 10.3389/fneur.2023.1115325. eCollection 2023.
2
Masson Tumor of the Central Nervous System: A Case Report and Review of Literature.中枢神经系统 Masson 瘤:病例报告及文献复习。
Am J Case Rep. 2022 Dec 21;23:e937597. doi: 10.12659/AJCR.937597.