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1
Bilateral paramedian pontine infarcts: a rare cause of bilateral horizontal gaze palsy.双侧脑桥旁正中梗死:双侧水平凝视麻痹的罕见病因。
BMJ Case Rep. 2019 Oct 31;12(10):e229503. doi: 10.1136/bcr-2019-229503.
2
Bilateral, vertical supranuclear gaze palsy following unilateral midbrain infarct.单侧中脑梗死继发双侧垂直性核上性凝视麻痹
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3
[Persistent lateral gaze palsy and abducens nerve palsy due to pontine infarction].[脑桥梗死所致持续性侧视麻痹和展神经麻痹]
Rinsho Shinkeigaku. 1998 Apr;38(4):344-6.
4
Bilateral horizontal gaze palsy with pontine cavernous hemangioma: a case report.
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Paramedian pontine infarction. Neurological/topographical correlation.脑桥旁正中梗死。神经学/地形学相关性。
Stroke. 1997 Apr;28(4):809-15. doi: 10.1161/01.str.28.4.809.
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Case Report: Bilateral Horizontal Gaze Palsy (1 + 1 Syndrome): A Supranuclear Gaze Palsy.病例报告:双侧水平凝视麻痹(1 + 1综合征):一种核上性凝视麻痹。
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本文引用的文献

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Central ocular motor disorders, including gaze palsy and nystagmus.中枢性眼球运动障碍,包括凝视麻痹和眼球震颤。
J Neurol. 2014 Sep;261 Suppl 2(Suppl 2):S542-58. doi: 10.1007/s00415-014-7385-9.
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Downbeat nystagmus associated with damage to the medial longitudinal fasciculus of the pons: a vestibular balance control mechanism via the lower brainstem paramedian tract neurons.与桥脑被盖内侧纵束损伤相关的低频摆动性眼震:通过脑桥下部中轴旁正中径路神经元的前庭平衡控制机制。
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Bilateral sixth nerve palsy.双侧展神经麻痹。
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Abducens nucleus syndrome due to pontine haemorrhage.
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Complete bilateral horizontal gaze paralysis disclosing multiple sclerosis.完全性双侧水平凝视麻痹提示多发性硬化症。
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7
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Stroke. 1997 Apr;28(4):809-15. doi: 10.1161/01.str.28.4.809.
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双侧脑桥旁正中梗死:双侧水平凝视麻痹的罕见病因。

Bilateral paramedian pontine infarcts: a rare cause of bilateral horizontal gaze palsy.

作者信息

Chernov Dmitriy, Karavassilis Maria Elizabeth, Hassan Farida, Bhandari Mohit

机构信息

Acute Medicine, Watford General Hospital, Watford, UK

Gastroenterology, Watford General Hospital, Watford, Hertfordshire, UK.

出版信息

BMJ Case Rep. 2019 Oct 31;12(10):e229503. doi: 10.1136/bcr-2019-229503.

DOI:10.1136/bcr-2019-229503
PMID:31676501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6827796/
Abstract

A 73-year-old man presented to accident and emergency with headache and diplopia. Examination of the eye movements revealed a bilateral complete horizontal gaze palsy. On admission, a CT scan of the brain was performed, which was unremarkable. An MRI of the brain was then performed, which confirmed tiny acute infarcts involving the pons and the right cerebellum. This man was promptly treated with aspirin 300 mg one time per day, as per the stroke pathway. Further diagnostic workup later revealed atrial flutter. This man was therefore commenced on apixaban. The differential diagnoses for bilateral gaze palsy include the following: multiple sclerosis, infarction, haemorrhage and space occupying lesion. Bilateral gaze palsy is often associated with other neurological symptoms.

摘要

一名73岁男性因头痛和复视前往急诊。眼部运动检查发现双侧完全性水平凝视麻痹。入院时进行了脑部CT扫描,结果无异常。随后进行了脑部MRI检查,证实脑桥和右侧小脑有微小急性梗死灶。按照中风治疗流程,该男子立即开始每天服用一次300毫克阿司匹林。进一步的诊断检查后来发现了心房扑动。因此,该男子开始服用阿哌沙班。双侧凝视麻痹的鉴别诊断包括以下几种:多发性硬化、梗死、出血和占位性病变。双侧凝视麻痹常伴有其他神经症状。