From the Intermountain Healthcare Medical Group, Salt Lake City, Utah, USA; University of Ottawa, Ottawa, Ontario, Canada; University of California, Los Angeles (UCLA), California, USA; Women's College Hospital, University of Toronto, Toronto, Ontario, Canada; University of Florida College of Medicine, Jacksonville, Florida, USA.
C. Bakewell has received consultancy fees from and/or served on speakers bureaus for AbbVie and Novartis Pharmaceuticals Corp. S.Z. Aydin has received honoraria from Novartis. V.K. Ranganath has served on the Data and Safety Monitoring Board for Amgen and has received grants for investigator-initiated studies from Mallinckrodt. L. Eder has received research or educational grants and/or consultancy fees from Novartis. G.S. Kaeley has received consultancy fees from Novartis.
J Rheumatol. 2020 Jul 1;47(7):973-982. doi: 10.3899/jrheum.190512. Epub 2019 Nov 1.
Psoriatic arthritis (PsA) affects up to 30% of patients with psoriasis and may include musculoskeletal manifestations such as enthesitis. Enthesitis is associated with joint damage, and early detection and treatment are essential to management of the disease. Traditionally assessed by clinical examination and conventional radiography, entheseal inflammation can now be more accurately assessed earlier in the disease using techniques such as ultrasound, magnetic resonance imaging, computed tomography, and molecular imaging. However, there is little consensus on the optimum definition for diagnosing enthesitis in PsA or on the ideal scoring system for measuring response to treatment. This review aims to summarize the benefits and limitations of different imaging modalities in the assessment of enthesitis. It also proposes that adoption of standardized definitions and validation of scoring systems and imaging techniques in clinical trials will allow the efficacy of new treatment options to be assessed more accurately.
银屑病关节炎（PsA）可影响多达 30%的银屑病患者，可能包括肌腱附着点炎等肌肉骨骼表现。肌腱附着点炎与关节损伤有关，早期发现和治疗对于疾病的管理至关重要。传统上通过临床检查和常规放射摄影评估，现在可以使用超声、磁共振成像、计算机断层扫描和分子成像等技术更早地更准确地评估附着点炎症。然而，对于在 PsA 中诊断肌腱附着点炎的最佳定义或测量治疗反应的理想评分系统，尚无共识。本综述旨在总结不同成像方式在评估肌腱附着点炎方面的优缺点。它还提出，在临床试验中采用标准化的定义和评分系统以及成像技术的验证，将使新的治疗选择的疗效能够更准确地评估。
