Bhagat Indira, Sarkar Subrata
Division of Neonatal-Perinatal Medicine, Wayne State University, Children's Hospital of Michigan, Detroit, MI.
Division of Neonatal-Perinatal Medicine, University of Michigan Health System, Ann Arbor, MI.
Neoreviews. 2019 Nov;20(11):e653-e660. doi: 10.1542/neo.20-11-e653.
The main purpose of therapeutic cooling is neuroprotection of asphyxiated infants with significant hypoxic-ischemic encephalopathy. However, to improve the overall outcome, it is necessary to properly manage the full range of multiple organ system complications found in asphyxiated infants undergoing therapeutic cooling. Every physiologic process in an asphyxiated infant can potentially be affected by the cooling treatment. The purpose of this review is to discuss the effect of cooling on neonatal physiology in the current recommended cooling range and the management thereof.
治疗性降温的主要目的是对患有严重缺氧缺血性脑病的窒息婴儿进行神经保护。然而，为了改善总体预后，妥善处理接受治疗性降温的窒息婴儿出现的多器官系统并发症至关重要。窒息婴儿的每一个生理过程都可能受到降温治疗的影响。本综述的目的是讨论在当前推荐的降温范围内降温对新生儿生理的影响及其管理。
