Fujita M, Sasayama S, Ejiri M, Asanoi H, Nakajima H, Miwa K
Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.
Clin Cardiol. 1988 Aug;11(8):525-8. doi: 10.1002/clc.4960110804.
In 31 patients without a history of preinfarction angina, coronary collateral circulation to the completely obstructed coronary artery was evaluated by coronary angiography during a convalescent period of their first myocardial infarction. Collateral visualization (collateral index) was found to be significantly greater in patients with involvement of the right coronary artery (2.1 +/- 1.1, SD) than in those with obstruction of the left anterior descending coronary artery (1.2 +/- 1.0, p less than 0.05). The time interval from the onset of symptoms of acute myocardial infarction to angiographic evaluation did not affect the extent of collateral visualization or the degree of coronary artery disease. These findings indicate that the collateral vessels develop after acute myocardial infarction regardless of the extent of coronary artery disease and accomplish the proliferative process within one month. It is also suggested that the collateral visualization is dependent on the size of perfusion territory of the infarct-related coronary artery.
在31例无前壁心肌梗死病史的患者中，于首次心肌梗死恢复期通过冠状动脉造影评估完全阻塞冠状动脉的侧支循环情况。结果发现，右冠状动脉受累患者的侧支显影（侧支指数）显著高于左前降支冠状动脉阻塞患者（分别为2.1±1.1和1.2±1.0，p<0.05）。从急性心肌梗死症状发作到造影评估的时间间隔，并不影响侧支显影程度或冠状动脉疾病的严重程度。这些发现表明，急性心肌梗死后侧支血管会发育，且与冠状动脉疾病严重程度无关，并在一个月内完成增殖过程。还提示侧支显影取决于梗死相关冠状动脉的灌注区域大小。
