Gregor P, Widimský P, Cervenka V, Vísek V, Sládková T, Dvorák J
2nd Department of Medicine, Charles University Medical School of Hygiene, Prague, Czechoslovakia.
Cor Vasa. 1988;30(3):177-85.
The aim of the study was to analyse the findings obtained in 27 patients with hypertrophic cardiomyopathy who lived to be 60 and more. Elderly patients are, more frequently than younger ones, women, mostly with a negative family history (81% vs. 30% in younger patients), with a lower incidence of syncope (11% vs. 25%), smaller myocardial wall thickness and lesser extent of hypertrophy. Elderly patients displayed mitral ring calcification more often (18%) than younger subjects (6%) or those of the same age but free of hypertrophic cardiomyopathy (3%). Pathological Q waves on the ECG recording were likewise less frequent (7.6% vs. 20.4%). While elderly patients exhibited manifest proneness to elevated values of left ventricular end-diastolic pressure, there were no marked differences in obstruction.
该研究的目的是分析27例年龄达到或超过60岁的肥厚型心肌病患者的研究结果。老年患者比年轻患者更常见的是女性，大多有阴性家族史（81%对比年轻患者的30%），晕厥发生率较低（11%对比25%），心肌壁厚度较小且肥厚程度较轻。老年患者二尖瓣环钙化的发生率（18%）高于年轻受试者（6%）或同年龄但无肥厚型心肌病的患者（3%）。心电图记录上的病理性Q波同样较少见（7.6%对比20.4%）。虽然老年患者明显倾向于左心室舒张末期压力升高，但在梗阻方面没有显著差异。
