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Guidelines for using antiretroviral agents among HIV-infected adults and adolescents. Recommendations of the Panel on Clinical Practices for Treatment of HIV.HIV 感染成人和青少年抗逆转录病毒药物使用指南。HIV 治疗临床实践小组的建议。
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Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLA-B*35Px Renders them to an Exhausted Phenotype in HIV-1 infection.在 HIV-1 感染中，HLA-B*35Px 限制的 CD8+T 细胞上 CTLA-4 的选择性上调使它们呈现出衰竭表型。
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Switching to Integrase Inhibitors Unlinked to Weight Increase in Perinatally HIV-Infected Young Adults and Adolescents: A 10-Year Observational Study.转换为与围产期感染艾滋病毒的青年和青少年体重增加无关的整合酶抑制剂：一项为期10年的观察性研究。
Microorganisms. 2020 Jun 8;8(6):864. doi: 10.3390/microorganisms8060864.

本文引用的文献

1
HIV-mediated immune aging in young adults infected perinatally or during childhood.HIV 介导的围生期或儿童期感染的年轻人免疫衰老。
AIDS. 2019 Sep 1;33(11):1705-1710. doi: 10.1097/QAD.0000000000002275.
2
Atorvastatin restricts HIV replication in CD4+ T cells by upregulation of p21.阿托伐他汀通过上调p21来限制HIV在CD4+ T细胞中的复制。
AIDS. 2016 Jan;30(2):171-83. doi: 10.1097/QAD.0000000000000917.
3
Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center.纪念斯隆凯特琳癌症中心接受伊匹单抗治疗的黑色素瘤患者的免疫相关不良事件、全身免疫抑制需求及其对生存和治疗失败时间的影响
J Clin Oncol. 2015 Oct 1;33(28):3193-8. doi: 10.1200/JCO.2015.60.8448. Epub 2015 Aug 17.
4
Naive T lymphocytes and recent thymic emigrants are associated with HIV-1 disease history in french adolescents and young adults infected in the perinatal period: the ANRS-EP38-IMMIP study.在围产期感染 HIV-1 的法国青少年和年轻成年人中，幼稚 T 淋巴细胞和近期胸腺迁出细胞与 HIV-1 疾病史相关：ANRS-EP38-IMMIP 研究。
Clin Infect Dis. 2014 Feb;58(4):573-87. doi: 10.1093/cid/cit729. Epub 2013 Nov 18.
5
As good as it gets? The problem of HIV persistence despite antiretroviral drugs.尽管有抗逆转录病毒药物，但 HIV 仍持续存在的问题。
Cell Host Microbe. 2012 Aug 16;12(2):132-8. doi: 10.1016/j.chom.2012.07.005.
6
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy.HIV 通过细胞间传播，即使在抗逆转录病毒治疗的情况下，仍允许持续复制。
Nature. 2011 Aug 17;477(7362):95-8. doi: 10.1038/nature10347.

Profound immune consequences for young adults infected with HIV perinatally or during childhood: a cautionary tale regarding adherence to antiretroviral therapy.

作者信息

Williams Dionna W, Elahi Shokrollah

机构信息

aDepartment of Molecular and Comparative Pathobiology bDivision of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA cDepartment of Dentistry, Faculty of Medicine and Dentistry dDepartment of Medical Microbiology and Immunology eFaculty of Medicine and Dentistry, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada.

出版信息

AIDS. 2019 Nov 15;33(14):2251-2252. doi: 10.1097/QAD.0000000000002328.

DOI:10.1097/QAD.0000000000002328
PMID:31688041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6839777/
Abstract
摘要