Saito Yuhi, Watanabe Toshiyuki, Sasaki Toshiyuki, Watanabe Kenichi, Hirayama Masao, Fujita Naoko
Kameda Seika Co., Ltd, Konan-ku, Niigata, Japan.
Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Akiha-ku, Niigata, Japan.
Biosci Biotechnol Biochem. 2020 Feb;84(2):365-371. doi: 10.1080/09168451.2019.1687282. Epub 2019 Nov 5.
Rice with double mutation of and (/) has much higher amounts of apparent amylose and resistant starch (RS) than usual varieties. In this study, we conducted two randomized, single-blind, crossover trials to investigate the effect of single ingestion of two processed foods composed of / mutant rice on postprandial blood glucose and insulin response in healthy adults, compared to those of usual cultivar. In trial 1, of ingestion of rice crackers, the incremental area under the curves of glucose (IAUCglc) and insulin (IAUCins) in RS group was significantly lower than in the control group. In trial 2, of the ingestion of cooked rice, IAUCglc in the RS group was significantly lower than in the control group. These results showed that the /-mutant rice cracker and cooked rice having high RS can attenuate postprandial blood glucose and insulin response.
具有 和 双突变的水稻(/)的表观直链淀粉和抗性淀粉(RS)含量比普通品种高得多。在本研究中,我们进行了两项随机、单盲、交叉试验,以研究与普通品种相比单次摄入由/突变水稻制成的两种加工食品对健康成年人餐后血糖和胰岛素反应的影响。在试验1中,对于米饼的摄入,RS组葡萄糖(IAUCglc)和胰岛素(IAUCins)的曲线下增量面积显著低于对照组。在试验2中,对于米饭的摄入,RS组的IAUCglc显著低于对照组。这些结果表明,具有高RS的/-突变体米饼和米饭可以减弱餐后血糖和胰岛素反应。