Scholtmeijer R J, van Unnik A M, ten Kate F W
Department of Pediatric Urology, Erasmus University Hospital, Rotterdam, The Netherlands.
Eur Urol. 1988;14(5):412-3. doi: 10.1159/000472994.
The authors describe an 11-month-old boy with acute urine retention due to fibromatosis. Cystoscopic examination revealed no abnormalities in the bladder but intraurethrally there was an impression of the lobi prostate. Repeated transurethral and transperineal biopsies showed proliferation of randomly arranged spindle cells in a loose collagenous matrix. Mitotic figures were scarce. Fibrous proliferations of the prostate and bladder are rare. The fibromatoses constitute a group of nonmetastasizing fibrous growths which tend to invade surrounding tissues. They show a wide range in histological appearance and biological behavior, varying from spontaneous regression to aggressive and destructive local growth. As in our case the histopathological diagnosis was fibromatosis without any further specification, it was impossible to predict the behavior of the process. For this reason, a wait-and-see policy was adopted: after a very short period of time, the tumor regressed spontaneously.
作者描述了一名11个月大因纤维瘤病导致急性尿潴留的男孩。膀胱镜检查显示膀胱无异常，但尿道内有前列腺叶的压痕。经尿道和经会阴反复活检显示，在疏松的胶原基质中有随机排列的梭形细胞增殖。有丝分裂象少见。前列腺和膀胱的纤维增生罕见。纤维瘤病是一组不发生转移的纤维性生长物，倾向于侵犯周围组织。它们在组织学表现和生物学行为上差异很大，从自发消退到侵袭性和破坏性的局部生长不等。正如我们病例中的组织病理学诊断为纤维瘤病但未作进一步明确一样，无法预测该病程的行为。因此，采取了观察等待的策略：在很短一段时间后，肿瘤自发消退。
