Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Chem Commun (Camb). 2019 Dec 4;55(93):14007-14010. doi: 10.1039/c9cc07348e. Epub 2019 Nov 6.
Cyanamide functionalised carbon nitride powder is reported as a photocatalyst for direct Minisci-type coupling of heteroarenes with ethers, alcohols, and amides using atmospheric oxygen as the oxidant at room temperature. This mild protocol displays broad substrate scope, good functional group tolerance and the catalyst can be easily isolated and reused for several cycles. It thereby addresses the two major limitations of previously reported photoredox-mediated Minisci reactions: (i) use of expensive and potentially harmful non-recyclable photocatalysts, and (ii) requirement of a stoichiometric amount of strong chemical oxidant. Finally, using platinum as a co-catalyst with the carbon nitride allows this light-mediated reaction to generate two value-added products under an anaerobic atmosphere - functionalised heteroarenes and H fuel.
氰胺功能化氮化碳粉末被报道为一种光催化剂，可在室温下使用大气氧作为氧化剂，直接将杂芳烃与醚、醇和酰胺进行 Minisci 型偶联。该温和的反应条件具有广泛的底物范围、良好的官能团耐受性，并且催化剂易于分离并可重复使用多次。因此，它解决了先前报道的光氧化还原介导的 Minisci 反应的两个主要限制：（i）使用昂贵且潜在有害的不可回收光催化剂；（ii）需要化学计量的强氧化剂。最后，使用铂作为氮化碳的共催化剂，使得该光介导的反应在无氧气氛下生成两种有价值的产物——功能化杂芳烃和 H 燃料。
