Lab of Biosystem and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China.
Chem Commun (Camb). 2019 Dec 4;55(93):14015-14018. doi: 10.1039/c9cc07491k. Epub 2019 Nov 6.
We developed a novel fluorescence labelling method to track exosome internalization pathways in cells by confocal microscopy. The proposed method allows evaluation and comparison of the uptake pathways of exosomes originating from different cells, which would offer the potential for understanding the functions of exosomes in intercellular communication and their applications in drug delivery.
我们开发了一种新的荧光标记方法,通过共聚焦显微镜来追踪细胞内的外泌体内化途径。该方法可以评估和比较来自不同细胞的外泌体的摄取途径,这将有助于理解外泌体在细胞间通讯中的功能及其在药物传递中的应用。