Szecsi P B, Koch C, Foltmann B
Department of Clinical Chemistry, Hvidovre Hospital, Denmark.
FEBS Lett. 1988 Sep 26;238(1):101-4. doi: 10.1016/0014-5793(88)80234-5.
Human seminal pepsinogen C has been purified and compared with gastric pepsinogen C. The two zymogens cannot be distinguished by amino acid compositions and sequences of the first 28 N-terminal amino acid residues are identical. Apparent immunological identity is observed with polyclonal antisera. Monoclonal antibodies toward seminal pepsinogen C have been produced. One is able to recognize a non-carbohydrate antigenic determinant only present in seminal pepsinogen C.
人精浆胃蛋白酶原C已被纯化,并与胃胃蛋白酶原C进行了比较。这两种酶原无法通过氨基酸组成来区分,并且前28个N端氨基酸残基的序列是相同的。用多克隆抗血清观察到明显的免疫同一性。已制备出针对精浆胃蛋白酶原C的单克隆抗体。其中一种能够识别仅存在于精浆胃蛋白酶原C中的非碳水化合物抗原决定簇。