Kemali M
Z Mikrosk Anat Forsch. 1979;93(2):218-24.
The electron microscope has revealed a large variety of synaptic vesicles in the interpeduncular nucleus (ITP) of the frog "Rana esculenta". They vary in shape, size and electron density. There are two types of synapses which show only translucent spherical vesicles: in one type the vesicles are 40 nm, in the other type they are 70 nm in diameter. In other types of synapses the translucent vesicles may be mixed with those with dense core. Large granules, 160 nm in diameter, already reported in the ITP (KEMALI 1977a), are also shown as well as tiny flat mixed with large flat dense core vesicles of dumb-bell shape. Two types of axo-axonic synapses are illustrated while no crest synapses have been demonstrated. The results suggest that the afferents to the ITP might be more numerous than those reported in the literature or that--as in the case of the habenular afferents which consist of cholinergic and peptergic fibres--each projecting nucleus to the ITP has different types of fibres with more than one type of transmitter. Furthermore, due to the vesicles sizes, we may consider the ITP as a site in the vertebrate central nervous system where conventional neurotransmitter structures coexist with probable neurohumoral elements.
电子显微镜已揭示在食用蛙“Rana esculenta”的脚间核（ITP）中有大量各种各样的突触小泡。它们在形状、大小和电子密度方面各不相同。有两种类型的突触仅显示半透明球形小泡：一种类型中小泡直径为40纳米，另一种类型中小泡直径为70纳米。在其他类型的突触中，半透明小泡可能与有致密核心的小泡混合。在ITP中已报道过的直径为160纳米的大颗粒（凯马利，1977a）也有显示，还有与哑铃形大扁平致密核心小泡混合的微小扁平小泡。文中展示了两种类型的轴 - 轴突触，而未证实有嵴突触。结果表明，投射到ITP的传入神经可能比文献中报道的更多，或者——如同缰核传入神经由胆碱能和肽能纤维组成的情况一样——每个向ITP投射的核都有不同类型的纤维且含有不止一种类型的递质。此外，鉴于小泡的大小，我们可以将ITP视为脊椎动物中枢神经系统中传统神经递质结构与可能的神经体液成分共存的一个部位。
