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调强弧形全身照射技术的考量与调整:剂量学描述

Considerations and adaptions to the modulated arc total body irradiation technique: dosimetry description.

作者信息

Effeney Beth, Biggs Jennifer, Brady Carole, Pemberton Melanie, Sim Lucy, Pullar Andrew

机构信息

Radiation Oncology Princess Alexandra Hospital - Raymond Terrace, Metro South Health Service District, South Brisbane, Queensland, Australia.

出版信息

J Med Radiat Sci. 2019 Dec;66(4):284-291. doi: 10.1002/jmrs.363. Epub 2019 Nov 6.

DOI:10.1002/jmrs.363
PMID:31696648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6920691/
Abstract

Total body irradiation (TBI) is a complex treatment technique, which has been slow to transition to a three-dimensional (3D) planning approach. There is limited literature available providing a detailed description on methods to plan TBI on a 3D planning system. 3D planning using the modulated arc TBI (MATBI) technique is a complex process involving a significant number of quality assurance processes and scripts, due to more than 40 treatment beams and two patient positions. This article will focus on the workflow and technical planning aspects of our institution's MATBI technique and identify reasons for modifications made to the developing institution's original MATBI approach. Included is a description of specific simulation equipment, detailed explanation of the four-stage computing process including the role of scripting to standardise and streamline what is otherwise a complex number of steps. The information provided is specific to one centre's approach but shows the fundamental planning process and demonstrates a streamlined method, which can be adapted to other planning systems. Overall, the ability to accurately represent the TBI technique in 3D on a planning system will be shown.

摘要

全身照射(TBI)是一种复杂的治疗技术,向三维(3D)计划方法的转变一直较为缓慢。关于在3D计划系统上进行TBI计划的方法,现有文献中提供详细描述的很少。由于有40多个治疗射束和两个患者体位,使用调制弧形TBI(MATBI)技术进行3D计划是一个复杂的过程,涉及大量质量保证过程和脚本。本文将重点关注我们机构的MATBI技术的工作流程和技术计划方面,并确定对开发机构的原始MATBI方法进行修改的原因。内容包括特定模拟设备的描述、对四阶段计算过程的详细解释,包括脚本编写在规范和简化原本复杂的众多步骤方面的作用。所提供的信息特定于一个中心的方法,但展示了基本的计划过程并演示了一种可适用于其他计划系统的简化方法。总体而言,将展示在计划系统上以3D准确呈现TBI技术的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/fbf70349bb0a/JMRS-66-284-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/921b196f7212/JMRS-66-284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/e7b34ec64317/JMRS-66-284-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/bc829d9e33cf/JMRS-66-284-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/d6b98b349884/JMRS-66-284-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/4704d232cb8f/JMRS-66-284-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/ff0f05c5639c/JMRS-66-284-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/fbf70349bb0a/JMRS-66-284-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/921b196f7212/JMRS-66-284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/e7b34ec64317/JMRS-66-284-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/bc829d9e33cf/JMRS-66-284-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/d6b98b349884/JMRS-66-284-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/4704d232cb8f/JMRS-66-284-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/ff0f05c5639c/JMRS-66-284-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2124/6920691/fbf70349bb0a/JMRS-66-284-g007.jpg

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本文引用的文献

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J Med Imaging Radiat Sci. 2015 Dec;46(4):442-449. doi: 10.1016/j.jmir.2015.09.007.
2
Modification of a modulated arc total body irradiation technique: Implementation and first clinical experience for paediatric patients.一种调制弧全身照射技术的改进:儿科患者的实施及首次临床经验
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Dosimetric aspects of inverse-planned modulated-arc total-body irradiation.逆向计划调制弧全身照射的剂量学方面
传统容积调强弧形放疗(VMAT)全身照射(TBI)与新型同步整合全骨髓照射方法(SIMBa)VMAT TBI之间的剂量学评估。
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J Appl Clin Med Phys. 2021 Sep;22(9):123-142. doi: 10.1002/acm2.13355. Epub 2021 Jul 14.
Med Phys. 2012 Aug;39(8):5263-71. doi: 10.1118/1.4739250.
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