Bottos M, Stefani D, Dalla Barba B, Pettenà G, Fava Vizziello G M, Zorzi C, D'Este A
Department of Pediatrics, University of Padua, Italy.
Helv Paediatr Acta. 1988 Aug;43(1-2):15-24.
Mortality and long-term outcome in low birthweight infants (less than or equal to 1500 g) treated in the neonatal intensive care unit of the Department of Pediatrics of the University of Padua in 1975, 1978/79, and 1983 were analysed. Mortality rates fell from 75% in 1975 to 58% in 1978/79 and to 33% in 1983. Incidence of sequelae decreased from 1975 to 1978/79 and did not change between 1978/79 and 1983. No perinatal pathology (RDS, hyperbilirubinemia, endocranial hemorrhage) was statistically related with long-term outcome, but some associations (RDS + endocranial hemorrhage + seizures) appeared more frequently in cases which presented major neurological sequelae.
对1975年、1978/79年和1983年在帕多瓦大学儿科学系新生儿重症监护病房接受治疗的低出生体重婴儿（小于或等于1500克）的死亡率和长期预后进行了分析。死亡率从1975年的75%降至1978/79年的58%，并在1983年降至33%。后遗症的发生率在1975年至1978/79年期间有所下降，在1978/79年至1983年期间没有变化。没有围产期病理（呼吸窘迫综合征、高胆红素血症、颅内出血）与长期预后存在统计学关联，但一些关联（呼吸窘迫综合征+颅内出血+癫痫发作）在出现严重神经后遗症的病例中更为常见。
