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从产前队列研究 Project Viva 中婴儿期到青春期纵向喘息表型的特征。

Characterization of longitudinal wheeze phenotypes from infancy to adolescence in Project Viva, a prebirth cohort study.

机构信息

Division of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Mass.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Mass.

出版信息

J Allergy Clin Immunol. 2020 Feb;145(2):716-719.e8. doi: 10.1016/j.jaci.2019.10.026. Epub 2019 Nov 6.

Abstract

Using data from infancy to adolescence, our analysis of longitudinal wheeze phenotypes allowed us to visualize four longitudinal wheeze trajectories (never/infrequent wheeze, mid-childhood onset wheeze, early transient wheeze, and persistent wheeze).

摘要

利用从婴儿期到青春期的数据,我们对纵向喘息表型的分析使我们能够可视化出四种纵向喘息轨迹(从未/偶尔喘息、儿童中期发作性喘息、早期一过性喘息和持续性喘息)。

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本文引用的文献

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Lessons from ten years of genome-wide association studies of asthma.哮喘全基因组关联研究十年的经验教训。
Clin Transl Immunology. 2017 Dec 15;6(12):e165. doi: 10.1038/cti.2017.54. eCollection 2017 Dec.
4
Sex-specific risk factors for childhood wheeze and longitudinal phenotypes of wheeze.儿童喘息的性别特异性危险因素及喘息的纵向表型
J Allergy Clin Immunol. 2016 Dec;138(6):1561-1568.e6. doi: 10.1016/j.jaci.2016.04.005. Epub 2016 Apr 27.
6
Infant wheeze, comorbidities and school age asthma.婴儿喘息、合并症与学龄期哮喘。
Pediatr Allergy Immunol. 2014 Jun;25(4):380-6. doi: 10.1111/pai.12223. Epub 2014 Apr 11.
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Cohort profile: project viva.队列简介:项目答辩。
Int J Epidemiol. 2015 Feb;44(1):37-48. doi: 10.1093/ije/dyu008. Epub 2014 Mar 16.
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Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA.比较 2 个出生队列儿童喘息表型:ALSPAC 和 PIAMA。
J Allergy Clin Immunol. 2011 Jun;127(6):1505-12.e14. doi: 10.1016/j.jaci.2011.02.002. Epub 2011 Mar 16.

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