Characterization of chloride uptake in Drosophila Kc cells.

作者信息

Sherwood A C, John-Alder K, Sanders M M

机构信息

Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854.

出版信息

J Cell Physiol. 1988 Sep;136(3):500-6. doi: 10.1002/jcp.1041360315.

Drosophila Kc cells use at least two mechanisms for chloride uptake. These transport systems can be distinguished by their kinetic properties and by their differential sensitivity to various drugs. One transport system predominates at [Cl-]o below 30 mM and is greater than fivefold more sensitive to disulfonic stilbenes than the second system. At [Cl-]o above 30 mM, the predominant uptake mechanism is inhibited by vanadate and nitrate.